Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 14/20 | 0.47 |
| ▸ | CA2 | P00918 | 14/20 | 0.47 |
| ▸ | CA9 | Q16790 | 12/20 | 0.44 |
| ▸ | CA7 | P43166 | 7/20 | 0.44 |
| ▸ | CA4 | P22748 | 7/20 | 0.44 |
| ▸ | CA12 | O43570 | 7/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28469591 | 0.85 | PRMT5 (0.47) | PRMT5WDR77KAT6A | |
| SCHEMBL21353039 | 0.85 | PRMT5 (0.47) | PRMT5WDR77KAT6A | |
| SCHEMBL28737824 | 0.84 | PSIP1 (0.41) | PRMT5WDR77KAT6A | |
| SCHEMBL28737773 | 0.82 | KAT6A (0.42) | KAT6A | |
| SCHEMBL28737771 | 0.82 | ADRB3 (0.41) | KAT6A | |
| SCHEMBL24154807 | 0.81 | CA2 (0.50) | CA1CA2CA9CA7CA4 | |
| SCHEMBL28468656 | 0.81 | POLB (0.46) | KAT6A | |
| SCHEMBL21353640 | 0.80 | ADRB3 (0.41) | PRMT5WDR77KAT6A | |
| SCHEMBL21353207 | 0.80 | ADRB3 (0.47) | PRMT5WDR77KAT6A | |
| SCHEMBL28737790 | 0.78 | ADRB3 (0.40) | PRMT5WDR77KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111699189-A | Modulators of beta-3 adrenergic receptors useful for the treatment or prevention of heart failure and disorders associated therewith | 艾尼纳制药公司 | 2020-09-22 | — | — | CN | disclosed |