Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.54 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MPL | P40238 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28474292 | 0.89 | EGFR (0.54) | EGFROXER1GAAMAPTTSHR | |
| SCHEMBL28472093 | 0.82 | OXER1 (0.61) | EGFROXER1GAAMAPTKMT2A | |
| SCHEMBL28987815 | 0.80 | MAPT (0.51) | EGFRMAPTMITFTSHRKMT2A | |
| SCHEMBL28468727 | 0.78 | OXER1 (0.63) | EGFROXER1GAAMAPTKMT2A | |
| SCHEMBL28474157 | 0.78 | RXFP1 (0.46) | EGFROXER1GAAMAPTKMT2A | |
| SCHEMBL28464941 | 0.78 | SIRT1 (0.61) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL28466204 | 0.78 | EGFR (0.45) | EGFROXER1TSHRPPARG | |
| SCHEMBL16240765 | 0.77 | MEN1 (0.47) | EGFRKMT2AMEN1 | |
| SCHEMBL10344755 | 0.74 | HTR2A (0.60) | EGFRMAPTKMT2AMEN1KDM4E | |
| SCHEMBL18509428 | 0.74 | EGFR (0.72) | EGFRGAAMAPTMITFKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109369647-B | Synthesis method of fused ring [1,2-a ] indole compound and 2, 3-disubstituted indole compound | 武汉大学 | 2020-09-08 | — | — | CN | disclosed |