Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28474292 | 0.86 | EGFR (0.54) | SIRT1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL28464941 | 0.84 | SIRT1 (0.61) | CYP1A2CYP2C19PPARGSIRT1KDM4E | |
| SCHEMBL28466204 | 0.84 | EGFR (0.45) | PPARGSIRT1FFAR1EGFROXER1 | |
| SCHEMBL28472093 | 0.80 | OXER1 (0.61) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL28468725 | 0.80 | ALDH1A1 (0.61) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL28469031 | 0.78 | EGFR (0.54) | PPARGKDM4EALDH1A1GAAMAPT | |
| SCHEMBL3194846 | 0.76 | LMNA (0.47) | RXFP1PRNPCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28468727 | 0.76 | OXER1 (0.63) | RXFP1KDM4EALDH1A1GAAMAPT | |
| SCHEMBL7231679 | 0.75 | PPARG (0.60) | PPARGKDM4EALDH1A1GAAMAPT | |
| SCHEMBL1345680 | 0.75 | NPSR1 (0.55) | RXFP1PRNPCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109369647-B | Synthesis method of fused ring [1,2-a ] indole compound and 2, 3-disubstituted indole compound | 武汉大学 | 2020-09-08 | — | — | CN | disclosed |