Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28469031 | 0.89 | EGFR (0.54) | EGFRKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL28466204 | 0.86 | EGFR (0.45) | EGFRTSHRSIRT1OXER1FFAR1 | |
| SCHEMBL28474157 | 0.86 | RXFP1 (0.46) | EGFRKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL28464941 | 0.86 | SIRT1 (0.61) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28472093 | 0.82 | OXER1 (0.61) | EGFRKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL28468725 | 0.82 | ALDH1A1 (0.61) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29160659 | 0.81 | KDM4E (0.71) | EGFRKDM4ERECQLALDH1A1MAPT | |
| SCHEMBL28987825 | 0.80 | MAPT (0.68) | KDM4ERECQLALDH1A1MAPTMEN1 | |
| SCHEMBL28468727 | 0.78 | OXER1 (0.63) | EGFRKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL7348472 | 0.77 | APEX1 (0.62) | EGFRKDM4ERECQLALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109369647-B | Synthesis method of fused ring [1,2-a ] indole compound and 2, 3-disubstituted indole compound | 武汉大学 | 2020-09-08 | — | — | CN | disclosed |