SCHEMBL28469554

SCHEMBL28469554

CC(C)(C)[Si](C)(C)O[C@H](COC(N)=O)C(=O)NN

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28468771 1.00 LMNA (0.30) LMNAHSD17B10
SCHEMBL28468773 1.00 LMNA (0.30) LMNAHSD17B10
SCHEMBL28463512 0.84
SCHEMBL22711177 0.76 CYP2D6 (0.35)
SCHEMBL22711197 0.76 CYP2D6 (0.35)
SCHEMBL22711173 0.76 CYP2D6 (0.35)
SCHEMBL28960243 0.74 ALOX15 (0.33) LMNAHSD17B10
SCHEMBL28943606 0.73 LMNA (0.33) LMNAHSD17B10
SCHEMBL28943607 0.73 LMNA (0.33) LMNAHSD17B10
SCHEMBL22711265 0.72 MEN1 (0.36) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111670187-B Beta-lactamase inhibitor and use thereof 苏州信诺维医药科技有限公司 2021-04-16 CN disclosed
CN-111670187-A Beta-lactamase inhibitor and use thereof 苏州信诺维医药科技有限公司 2020-09-15 CN disclosed