Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18625546 | 0.86 | CYP1A2 (0.35) | LMNACYP1A2SMN1; SMN2 | |
| SCHEMBL18341172 | 0.79 | LMNA (0.31) | ALOX15LMNAHSD17B10CYP1A2SMN1; SMN2 | |
| SCHEMBL18625595 | 0.79 | LMNA (0.31) | ALOX15LMNAHSD17B10CYP1A2SMN1; SMN2 | |
| SCHEMBL28943606 | 0.78 | LMNA (0.33) | ALOX15LMNAHSD17B10CYP1A2CYP2D6 | |
| SCHEMBL28943607 | 0.78 | LMNA (0.33) | ALOX15LMNAHSD17B10CYP1A2CYP2D6 | |
| SCHEMBL25379497 | 0.77 | LMNA (0.32) | ALOX15LMNAHSD17B10CYP1A2CYP2D6 | |
| SCHEMBL31047801 | 0.77 | LMNA (0.32) | ALOX15LMNAHSD17B10CYP1A2CYP2D6 | |
| SCHEMBL31031879 | 0.76 | CYP1A2 (0.31) | CYP1A2CYP2D6PKMSMN1; SMN2NPSR1 | |
| SCHEMBL28468773 | 0.74 | LMNA (0.30) | LMNAHSD17B10 | |
| SCHEMBL28469554 | 0.74 | LMNA (0.30) | LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115413275-A | Substituted 1,1 , -biphenyl compounds and methods of use thereof | 爱彼特生物制药公司 | 2022-11-29 | — | — | CN | disclosed |