Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.32 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28468100 | 0.83 | UCHL1 (0.36) | HSD17B10MAPK1KDM4EALDH1A1HPGD | |
| SCHEMBL28466869 | 0.78 | HSD17B10 (0.55) | MCL1GPR35HSD17B10MAPK1GFER | |
| SCHEMBL17560158 | 0.71 | HSD17B10 (0.59) | MCL1GPR35HSD17B10MAPK1GFER | |
| SCHEMBL20618017 | 0.70 | MCL1 (0.50) | MCL1GPR35HSD17B10MAPK1GFER | |
| SCHEMBL1830220 | 0.67 | LPL (0.35) | MAPK1USP30 | |
| SCHEMBL20448653 | 0.67 | DAO (0.34) | MCL1MAPK1ALDH1A1HPGDUSP30 | |
| SCHEMBL20563255 | 0.67 | USP30 (0.33) | USP30 | |
| SCHEMBL13721705 | 0.66 | MAPK1 (0.34) | MAPK1USP30 | |
| SCHEMBL20564062 | 0.65 | PTPN1 (0.34) | HSD17B10KDM4EALDH1A1HPGDUSP30 | |
| SCHEMBL793571 | 0.65 | LPL (0.40) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407854-B | Novel tetracyclic compounds | 北京加科思新药研发有限公司 | 2020-09-15 | — | — | CN | disclosed |