Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 10/20 | 0.95 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30945416 | 1.00 | ACHE (0.95) | ACHEBLMSMN1; SMN2TSHROPRM1 | |
| SCHEMBL1920707 | 0.98 | ACHE (1.00) | ACHEBLMSMN1; SMN2TSHROPRM1 | |
| Water SCHEMBL11727004 | 0.95 | ACHE (0.95) | ACHEBLMSMN1; SMN2TSHROPRM1 | |
| Iodide SCHEMBL29488102 | 0.95 | ACHE (0.95) | ACHEBLMSMN1; SMN2TSHROPRM1 | |
| Dimethylcarbate SCHEMBL4413046 | 0.81 | ACHE (0.69) | ACHEBLMSMN1; SMN2TSHROPRM1 | |
| Dimethylcarbate SCHEMBL4413044 | 0.80 | ACHE (0.67) | ACHEBLMSMN1; SMN2TSHROPRM1 | |
| SCHEMBL26628889 | 0.79 | ACHE (0.67) | ACHEBLMSMN1; SMN2TSHROPRM1 | |
| Edrophonium SCHEMBL34789 | 0.79 | ACHE (1.00) | ACHEBLMSMN1; SMN2TSHROPRM1 | |
| Edrophonium SCHEMBL19148596 | 0.79 | ACHE (1.00) | ACHEBLMSMN1; SMN2TSHROPRM1 | |
| Edrophonium SCHEMBL10893551 | 0.77 | ACHE (0.96) | ACHEBLMSMN1; SMN2TSHROPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113025309-A | Quantum dot, surface modification method thereof and quantum dot light-emitting diode | TCL集团股份有限公司 | 2021-06-25 | — | — | CN | claimed |
| CN-111793975-A | Antibacterial fabric and preparation method thereof | 上海封林贸易有限公司 | 2020-10-20 | — | — | CN | claimed |
| CN-113025309-A | Quantum dot, surface modification method thereof and quantum dot light-emitting diode | TCL集团股份有限公司 | 2021-06-25 | — | — | CN | disclosed |
| CN-111809392-A | Antibacterial underwear and preparation method thereof | 上海封林贸易有限公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-111793975-A | Antibacterial fabric and preparation method thereof | 上海封林贸易有限公司 | 2020-10-20 | — | — | CN | disclosed |