Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18130855 | 0.97 | ACHE (0.55) | ACHEL3MBTL1ALDH1A1TSHRKDM4E | |
| SCHEMBL29852164 | 0.97 | ACHE (0.55) | ACHEL3MBTL1ALDH1A1TSHRKDM4E | |
| SCHEMBL14363150 | 0.89 | CYP1A2 (0.46) | ACHEALDH1A1TSHRKDM4EMAPT | |
| SCHEMBL28879153 | 0.85 | ACHE (0.65) | ACHEL3MBTL1ALDH1A1TSHRCTNNB1 | |
| SCHEMBL28469718 | 0.84 | ACHE (0.52) | ACHEL3MBTL1ALDH1A1TSHRKDM4E | |
| SCHEMBL6565869 | 0.83 | TSHR (0.68) | ALDH1A1TSHRKDM4EMAPTHTT | |
| SCHEMBL2565359 | 0.82 | ACHE (0.61) | ACHEL3MBTL1ALDH1A1TSHRKDM4E | |
| SCHEMBL30474574 | 0.82 | ACHE (0.61) | ACHEL3MBTL1ALDH1A1TSHRKDM4E | |
| SCHEMBL10961835 | 0.81 | L3MBTL1 (0.48) | ACHEL3MBTL1ALDH1A1KDM4ECTNNB1 | |
| SCHEMBL1598817 | 0.80 | SMN1; SMN2 (0.51) | L3MBTL1ALDH1A1KDM4EMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867833-A | Laundry compositions | 弗门尼舍有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-114829568-A | Perfume delivery system | 弗门尼舍有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114829567-A | Perfume formulations for delivery systems | 弗门尼舍有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-107666897-B | Microcapsules with high surface deposition | 弗门尼舍有限公司 | 2021-12-28 | — | — | CN | disclosed |
| CN-113747880-A | Hybrid microcapsules | 弗门尼舍有限公司 | 2021-12-03 | — | — | CN | disclosed |
| CN-113573804-A | Cleavable polyol-based microcapsules | 弗门尼舍有限公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-113557081-A | Poly (amide-ester) microcapsules | 弗门尼舍有限公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-113557082-A | Composite microcapsule | 弗门尼舍有限公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-113329811-A | Poly (ester urea) microcapsules | 弗门尼舍有限公司 | 2021-08-31 | — | — | CN | disclosed |
| CN-113329812-A | Method for preparing microcapsules | 弗门尼舍有限公司 | 2021-08-31 | — | — | CN | disclosed |
| CN-113226532-A | Polyamide microcapsules | 弗门尼舍有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-113195091-A | Method for producing polyamide microcapsules | 弗门尼舍有限公司 | 2021-07-30 | — | — | CN | disclosed |
| CN-107427807-B | Process for preparing polyurea microcapsules | 弗门尼舍有限公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-111918714-A | Method for preparing microcapsules | 弗门尼舍有限公司 | 2020-11-10 | — | — | CN | disclosed |
| CN-111886071-A | Method for preparing mineralized microcapsules | 弗门尼舍有限公司 | 2020-11-03 | — | — | CN | disclosed |
| CN-111801155-A | Method for preparing microcapsules | 弗门尼舍有限公司 | 2020-10-20 | — | — | CN | disclosed |