SCHEMBL2565359

SCHEMBL2565359

COC(=O)Oc1ccc(C)cc1OC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.61
ALDH1A1 P00352 4/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
ABL1 P00519 1/20 0.49
RIN1 Q13671 1/20 0.49
EPHX1 P07099 1/20 0.49
MAPT P10636 6/20 0.49
HTT P42858 3/20 0.48
HSP90AA1 P07900 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
SMN1; SMN2 Q16637 3/20 0.47
KDM4E B2RXH2 1/20 0.47
JAK2 O60674 1/20 0.47
GAA P10253 1/20 0.47
LMNA P02545 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
MAPK1 P28482 1/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30474574 1.00 ACHE (0.61) ACHEALDH1A1L3MBTL1ABL1RIN1
SCHEMBL2564649 0.93 ACHE (0.61) ACHEALDH1A1L3MBTL1ABL1RIN1
SCHEMBL28879153 0.92 ACHE (0.65) ACHEALDH1A1L3MBTL1ABL1RIN1
SCHEMBL29852164 0.84 ACHE (0.55) ACHEALDH1A1L3MBTL1ABL1RIN1
SCHEMBL18130855 0.84 ACHE (0.55) ACHEALDH1A1L3MBTL1ABL1RIN1
SCHEMBL17355769 0.84 KDM4E (0.46) ACHEALDH1A1L3MBTL1EPHX1MAPT
SCHEMBL18230979 0.83 ACHE (0.42) ACHEALDH1A1L3MBTL1MAPTHTT
SCHEMBL171836 0.83 TSHR (0.64) ACHEALDH1A1L3MBTL1MAPTHTT
SCHEMBL1598721 0.83 L3MBTL1 (0.56) ACHEALDH1A1L3MBTL1MAPTHTT
SCHEMBL21991471 0.83 SMN1; SMN2 (0.51) EPHX1MAPTHTTSMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 250 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4519404-A1 METHODS FOR ENHANCING MENTAL PERFORMANCE AND COMPOSITIONS FOR USE THEREIN Firmenich SA (CH) 2025-03-12 EP claimed
EP-4514477-A1 FRAGRANCE COMPOSITIONS HAVING LONG-LASTING TRAIL PERFORMANCE Firmenich SA (CH) 2025-03-05 EP claimed
WO-2023247599-A1 FRAGRANCE COMPOSITIONS HAVING LONG-LASTING TRAIL PERFORMANCE FIRMENICH SA (CH) 2023-12-28 WO claimed
WO-2023247604-A1 METHODS FOR ENHANCING MENTAL PERFORMANCE AND COMPOSITIONS FOR USE THEREIN FIRMENICH SA (CH) 2023-12-28 WO claimed
CN-107206343-B Microcapsules imparting strong vanilla odor notes 弗门尼舍有限公司 2021-02-05 CN claimed
US-10260022-B2 Microcapsules imparting intense vanilla odor note FIRMENICH SA (CH) 2019-04-16 US claimed
EP-3253455-B1 MICROCAPSULES IMPARTING INTENSE VANILLA ODOR NOTE FIRMENICH & CIE (CH) 2019-04-10 EP claimed
US-20180023033-A1 MICROCAPSULES IMPARTING INTENSE VANILLA ODOR NOTE FIRMENICH SA (CH) 2018-01-25 US claimed
US-9834739-B2 Fragrance composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2017-12-05 US claimed
US-20160333291-A1 FRAGRANCE COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2016-11-17 US claimed
WO-2016124746-A1 MICROCAPSULES IMPARTING INTENSE VANILLA ODOR NOTE FIRMENICH SA (CH) 2016-08-11 WO claimed
US-8648033-B2 Organic carbonates with vanilla odor FIRMENICH SA (CH) 2014-02-11 US claimed
EP-2561051-B1 ORGANIC CARBONATES WITH VANILLA ODOR FIRMENICH & CIE (CH) 2013-12-18 EP claimed
EP-2561051-A1 ORGANIC CARBONATES WITH VANILLA ODOR Firmenich SA (CH) 2013-02-27 EP claimed
US-20130011352-A1 ORGANIC CARBONATES WITH VANILLA ODOR FIRMENICH SA (CH) 2013-01-10 US claimed
WO-2011132098-A1 ORGANIC CARBONATES WITH VANILLA ODOR FIRMENICH SA (CH) 2011-10-27 WO claimed
US-12616948-B2 Polyamide microcapsules FIRMENICH SA (CH) 2026-05-05 US disclosed
WO-2026087780-A1 CORE-SHELL MICROCAPSULES FIRMENICH SA (CH) 2026-04-30 WO disclosed
US-20130011352-A1 ORGANIC CARBONATES WITH VANILLA ODOR FIRMENICH SA (CH) 2013-01-10 US disclosed
WO-2011132098-A1 ORGANIC CARBONATES WITH VANILLA ODOR FIRMENICH SA (CH) 2011-10-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130011352-A1 ORGANIC CARBONATES WITH VANILLA ODOR TRPV3, HVCN1, TRPV5 ACHE 1846/4885ALDH1A1 2125/4885L3MBTL1 4110/4885
US-12616948-B2 Polyamide microcapsules HDHD5, DDC, USP39 ACHE 2730/4885ALDH1A1 4007/4885L3MBTL1 2993/4885
US-10260022-B2 Microcapsules imparting intense vanilla odor note TRPC5, TRPV5, TRPM5 ACHE 213/4885ALDH1A1 1824/4885L3MBTL1 3439/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.