Fluoride

Fluoride

SCHEMBL28470652

F.[B](c1ccc[nH]1)c1ccc[nH]1

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DAO P14920 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
AURKA O14965 1/20 0.33
AURKB Q96GD4 1/20 0.33
INCENP Q9NQS7 1/20 0.33
FKBP5 Q13451 1/20 0.32
MCL1 Q07820 1/20 0.30
NAPRT Q6XQN6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL27732544 0.78 FKBP5 (0.31) FKBP5
SCHEMBL485899 0.63
Fluoride SCHEMBL28006656 0.61
Fluoride SCHEMBL27944277 0.59 MAOA (0.45) DAOHDAC8HDAC6AURKAAURKB
SCHEMBL30659527 0.58
Hydrochloric Acid SCHEMBL7988951 0.58 HDAC6 (0.40) DAOHDAC8HDAC6AURKAAURKB
Fluoride SCHEMBL29179319 0.57 MAOA (0.44) DAOHDAC8HDAC6AURKAAURKB
Fluoride SCHEMBL28214761 0.57 MAOA (0.44) DAOHDAC8HDAC6AURKAAURKB
SCHEMBL31512727 0.57
SCHEMBL145329 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108865113-B For detecting Fe3+、Co2+Naphthaldehyde-dipyrrole boron fluorine fluorescent molecular probe and preparation method thereof 德州学院 2020-10-30 CN disclosed