Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GCK | P35557 | 4/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | CCNK | O75909 | 1/20 | 0.31 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28891654 | 0.80 | PTGS2 (0.36) | — | |
| SCHEMBL28464756 | 0.79 | SMN1; SMN2 (0.43) | L3MBTL1SMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL27982877 | 0.77 | — | — | |
| SCHEMBL28477181 | 0.76 | OXTR (0.36) | L3MBTL1SMN1; SMN2KMT2ARAB9AHTT | |
| SCHEMBL27691368 | 0.70 | L3MBTL1 (0.42) | L3MBTL1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL28960954 | 0.68 | — | — | |
| SCHEMBL29813556 | 0.67 | KIT (0.38) | L3MBTL1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9069074 | 0.67 | SMN1; SMN2 (0.38) | L3MBTL1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL7697126 | 0.66 | — | — | |
| SCHEMBL31192843 | 0.66 | KDM5A (0.46) | L3MBTL1SMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808024-B | Phenyl pyrazolone compound or salt thereof, preparation method and application | 郑州手性药物研究院有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-111808024-A | Phenylpyrazolone compound or salt thereof, preparation method and application | 郑州手性药物研究院有限公司 | 2020-10-23 | — | — | CN | disclosed |