Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | NQO2 | P16083 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30065110 | 0.90 | ALDH1A1 (0.69) | KDM4EALDH1A1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL1527016 | 0.90 | ALDH1A1 (0.69) | KDM4EALDH1A1SMN1; SMN2RAB9AMEN1 | |
| Acridine SCHEMBL37657 | 0.81 | ALDH1A1 (0.71) | KDM4EALDH1A1RAB9AMEN1POLB | |
| Acridine SCHEMBL1006962 | 0.81 | ALDH1A1 (0.71) | KDM4EALDH1A1RAB9AMEN1POLB | |
| SCHEMBL31414248 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL1408871 | 0.80 | ALDH1A1 (0.69) | KDM4EALDH1A1SMN1; SMN2RAB9AMEN1 | |
| Isothiocyanate SCHEMBL27973950 | 0.79 | NQO2 (0.53) | KDM4EALDH1A1SMN1; SMN2RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL21816611 | 0.78 | ALDH1A1 (0.67) | KDM4EALDH1A1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL15010571 | 0.74 | NQO2 (1.00) | KDM4EALDH1A1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL31414245 | 0.72 | TLR8 (0.53) | KDM4EALDH1A1SMN1; SMN2RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250182-B | 1, 8-naphthamide (2-R group acridine group) thiourea silver ion probe and preparation method thereof | 广西中医药大学 | 2020-10-23 | — | — | CN | disclosed |