Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 2/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 2/20 | 1.00 |
| ▸ | GBA1 | P04062 | 1/20 | 1.00 |
| ▸ | CNR1 | P21554 | 1/20 | 1.00 |
| ▸ | TBXA2R | P21731 | 1/20 | 1.00 |
| ▸ | HRH2 | P25021 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.97 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.97 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.97 |
| ▸ | TSHR | P16473 | 1/20 | 0.97 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ambroxol SCHEMBL7855003 | 1.00 | CYP2D6 (1.00) | CYP2D6SLC6A4KCNH2LMNACYP1A2 | |
| Ambroxol SCHEMBL423712 | 1.00 | CYP2D6 (1.00) | CYP2D6SLC6A4KCNH2LMNACYP1A2 | |
| Ambroxol SCHEMBL18702 | 1.00 | CYP2D6 (1.00) | CYP2D6SLC6A4KCNH2LMNACYP1A2 | |
| Ambroxol SCHEMBL29380194 | 1.00 | CYP2D6 (1.00) | CYP2D6SLC6A4KCNH2LMNACYP1A2 | |
| Ambroxol SCHEMBL99455 | 0.99 | CYP3A4 (1.00) | CYP2D6SLC6A4KCNH2LMNACYP1A2 | |
| Ambroxol SCHEMBL6601413 | 0.99 | CYP3A4 (1.00) | CYP2D6SLC6A4KCNH2LMNACYP1A2 | |
| Ambroxol SCHEMBL1648757 | 0.97 | CYP2D6 (0.94) | CYP2D6SLC6A4KCNH2LMNACYP1A2 | |
| Ambroxol SCHEMBL11533052 | 0.93 | CYP2D6 (0.87) | CYP2D6SLC6A4KCNH2LMNACYP1A2 | |
| SCHEMBL24446418 | 0.92 | CYP2D6 (0.84) | CYP2D6SLC6A4KCNH2LMNACYP1A2 | |
| SCHEMBL22927201 | 0.92 | CYP2D6 (0.84) | CYP2D6SLC6A4KCNH2LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111732518-A | Preparation method of cis-4- [ (2-amino-3, 5-dibromobenzyl) amino ] cyclohexanol | 河北宇辰医药科技有限公司 | 2020-10-02 | — | — | CN | claimed |
| CN-114767628-B | Stable ambroxol hydrochloride injection and preparation method thereof | 海南灵康制药有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-114767628-A | Stable ambroxol hydrochloride injection and preparation method thereof | 海南灵康制药有限公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-112089688-A | Stable ambroxol hydrochloride injection and preparation method thereof | 康普药业股份有限公司 | 2020-12-18 | — | — | CN | disclosed |
| CN-111732518-A | Preparation method of cis-4- [ (2-amino-3, 5-dibromobenzyl) amino ] cyclohexanol | 河北宇辰医药科技有限公司 | 2020-10-02 | — | — | CN | disclosed |
| CN-111732518-A | Preparation method of cis-4- [ (2-amino-3, 5-dibromobenzyl) amino ] cyclohexanol | 河北宇辰医药科技有限公司 | 2020-10-02 | — | — | CN | disclosed |
| CN-111732518-A | Preparation method of cis-4- [ (2-amino-3, 5-dibromobenzyl) amino ] cyclohexanol | 河北宇辰医药科技有限公司 | 2020-10-02 | — | — | CN | disclosed |