Ambroxol

Ambroxol

SCHEMBL29380194

Nc1c(Br)cc(Br)cc1CN[C@H]1CC[C@H](O)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2D6 P10635 3/20 1.00
▸ SLC6A4 P31645 2/20 1.00
▸ KCNH2 Q12809 2/20 1.00
▸ LMNA P02545 2/20 1.00
▸ CYP1A2 P05177 2/20 1.00
▸ HIF1A Q16665 2/20 1.00
▸ GBA1 P04062 1/20 1.00
▸ CNR1 P21554 1/20 1.00
▸ TBXA2R P21731 1/20 1.00
▸ HRH2 P25021 1/20 1.00
▸ CYP3A4 P08684 2/20 0.97
▸ TDP1 Q9NUW8 2/20 0.97
▸ ALOX15 P16050 1/20 0.97
▸ TSHR P16473 1/20 0.97
▸ ABCB11 O95342 1/20 0.42
▸ ADORA3 P0DMS8 1/20 0.42
▸ AR P10275 1/20 0.42
▸ SLC6A2 P23975 1/20 0.42
▸ PDE4A P27815 1/20 0.42
▸ SLC6A3 Q01959 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ambroxol SCHEMBL28472066 1.00 CYP2D6 (1.00) CYP2D6SLC6A4KCNH2LMNACYP1A2
Ambroxol SCHEMBL7855003 1.00 CYP2D6 (1.00) CYP2D6SLC6A4KCNH2LMNACYP1A2
Ambroxol SCHEMBL423712 1.00 CYP2D6 (1.00) CYP2D6SLC6A4KCNH2LMNACYP1A2
Ambroxol SCHEMBL18702 1.00 CYP2D6 (1.00) CYP2D6SLC6A4KCNH2LMNACYP1A2
Ambroxol SCHEMBL99455 0.99 CYP3A4 (1.00) CYP2D6SLC6A4KCNH2LMNACYP1A2
Ambroxol SCHEMBL6601413 0.99 CYP3A4 (1.00) CYP2D6SLC6A4KCNH2LMNACYP1A2
Ambroxol SCHEMBL1648757 0.97 CYP2D6 (0.94) CYP2D6SLC6A4KCNH2LMNACYP1A2
Ambroxol SCHEMBL11533052 0.93 CYP2D6 (0.87) CYP2D6SLC6A4KCNH2LMNACYP1A2
SCHEMBL24446418 0.92 CYP2D6 (0.84) CYP2D6SLC6A4KCNH2LMNACYP1A2
SCHEMBL22927201 0.92 CYP2D6 (0.84) CYP2D6SLC6A4KCNH2LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12619005-B2 Optical film with improved optical properties, display apparatus comprising same, and manufacturing method therefor KOLON INDUSTRIES, INC. (KR) 2026-05-05 — — US claimed
EP-4178606-B1 THERAPEUTIC HYBRID MICRONEEDLE PATCH FOR THE DELIVERY OF INSULIN AND GLUCAGON THE REGENTS OF UNIV OF CALIFORNIA (US) 2025-09-17 — — EP claimed
EP-4304346-B1 AN AQUAFARMING TANK FOR GROWING WATER-LIVING SPECIES AND A METHOD OF CONSTRUCTING THE AQUAFARMING TANK FUERSTENBERG AMFI LTD (LV) 2025-04-30 — — EP claimed
CN-119770419-A Modified recombinant III type collagen hydrogel loaded with houttuynia cordata vesicles and application thereof 常州大学 2025-04-08 — — CN claimed
US-20240272140-A1 DIAGNOSIS AND TREATMENT OF FUSARIOSIS AND SCEDOSPORIOSIS THE BRIGHAM AND WOMEN'S HOSPITAL, INC. 2024-08-15 — — US claimed
US-20240058288-A1 DRUG COCKTAIL FOR TREATMENT OF PARKINSON'S DISEASE, LEWY BODY DISEASE AND MULTIPLE SYSTEM ATROPHY ALETA NEUROSCIENCE LLC (US) 2024-02-22 — — US claimed
EP-4304346-A1 AN AQUAFARMING TANK FOR GROWING WATER-LIVING SPECIES AND A METHOD OF CONSTRUCTING THE AQUAFARMING TANK Amfitop Aqua Farming Ltd. (LV) 2024-01-17 — — EP claimed
US-20230375750-A1 OPTICAL FILM WITH IMPROVED OPTICAL PROPERTIES, DISPLAY APPARATUS COMPRISING SAME, AND MANUFACTURING METHOD THEREFOR KOLON INDUSTRIES, INC. (KR) 2023-11-23 — — US claimed
US-20230240981-A1 THERAPEUTIC HYBRID MICRONEEDLE PATCH FOR THE DELIVERY OF INSULIN AND GLUCAGON THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-08-03 — — US claimed
EP-3498297-B1 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF AUTISM STALICLA S A (CH) 2023-06-21 — — EP claimed
EP-4178606-A1 THERAPEUTIC HYBRID MICRONEEDLE PATCH FOR THE DELIVERY OF INSULIN AND GLUCAGON The Regents of University of California (US) 2023-05-17 — — EP claimed
CN-115811985-A Therapeutic hybrid microneedle patch for delivery of insulin and glucagon 加利福尼亚大学董事会 2023-03-17 — — CN claimed
CN-115707459-A Synergistic composition of drug-resistant tumor treatment drugs 复旦大学 2023-02-21 — — CN claimed
WO-2022263321-A1 AN AQUAFARMING TANK FOR GROWING WATER-LIVING SPECIES AND A METHOD OF CONSTRUCTING THE AQUAFARMING TANK AMFITOP SOLID SURFACE PRODUCTS (LV) 2022-12-22 — — WO claimed
WO-2022224118-A1 DRUG COCKTAIL FOR TREATMENT OF PARKINSON'S DISEASE, LEWY BODY DISEASE AND MULTIPLE SYSTEM ATROPHY ALETA NEUROSCIENCE, LLC (US) 2022-10-27 — — WO claimed
US-20220331408-A1 TREATMENT OF GLYCOGEN STORAGE DISEASE (GSD) GENETHON (FR) 2022-10-20 — — US claimed
EP-3996696-A1 TREATMENT OF GLYCOGEN STORAGE DISEASE (GSD) Genethon (FR) 2022-05-18 — — EP claimed
CN-122055820-A Formulations comprising 3-amino-3-methyl-2-butanol and their use in electrical and electronic applications 安达伟胜股份有限公司 2026-05-15 — — CN disclosed
WO-2022021769-A1 AMBROXOL HYDROCHLORIDE ORAL SPRAY SOLUTION AND PREPARATION METHOD THEREFOR 德国吉麦医疗技术有限公司 2022-02-03 — — WO disclosed
WO-2022021769-A1 AMBROXOL HYDROCHLORIDE ORAL SPRAY SOLUTION AND PREPARATION METHOD THEREFOR 德国吉麦医疗技术有限公司 2022-02-03 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12619005-B2 Optical film with improved optical properties, display apparatus comprising same, and manufacturing method therefor SETDB1, TRAFD1, RFC5 CYP2D6 4636/4885SLC6A4 3304/4885KCNH2 4112/4885
US-20240058288-A1 DRUG COCKTAIL FOR TREATMENT OF PARKINSON'S DISEASE, LEWY BODY DISEASE AND MULTIPLE SYSTEM ATROPHY BAG3, BAG2, PHB1 CYP2D6 2282/4885SLC6A4 1391/4885KCNH2 2415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback