Ambroxol

Ambroxol

SCHEMBL423712

Nc1c(Br)cc(Br)cc1CNC1CCC(O)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP2D6 P10635 3/20 1.00
▸ SLC6A4 P31645 2/20 1.00
▸ KCNH2 Q12809 2/20 1.00
▸ LMNA P02545 2/20 1.00
▸ CYP1A2 P05177 2/20 1.00
▸ HIF1A Q16665 2/20 1.00
▸ GBA1 P04062 1/20 1.00
▸ CNR1 P21554 1/20 1.00
▸ TBXA2R P21731 1/20 1.00
▸ HRH2 P25021 1/20 1.00
▸ CYP3A4 P08684 2/20 0.97
▸ TDP1 Q9NUW8 2/20 0.97
▸ ALOX15 P16050 1/20 0.97
▸ TSHR P16473 1/20 0.97
▸ ABCB11 O95342 1/20 0.42
▸ ADORA3 P0DMS8 1/20 0.42
▸ AR P10275 1/20 0.42
▸ SLC6A2 P23975 1/20 0.42
▸ PDE4A P27815 1/20 0.42
▸ SLC6A3 Q01959 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ambroxol SCHEMBL28472066 1.00 CYP2D6 (1.00) CYP2D6SLC6A4KCNH2LMNACYP1A2
Ambroxol SCHEMBL7855003 1.00 CYP2D6 (1.00) CYP2D6SLC6A4KCNH2LMNACYP1A2
Ambroxol SCHEMBL18702 1.00 CYP2D6 (1.00) CYP2D6SLC6A4KCNH2LMNACYP1A2
Ambroxol SCHEMBL29380194 1.00 CYP2D6 (1.00) CYP2D6SLC6A4KCNH2LMNACYP1A2
Ambroxol SCHEMBL99455 0.99 CYP3A4 (1.00) CYP2D6SLC6A4KCNH2LMNACYP1A2
Ambroxol SCHEMBL6601413 0.99 CYP3A4 (1.00) CYP2D6SLC6A4KCNH2LMNACYP1A2
Ambroxol SCHEMBL1648757 0.97 CYP2D6 (0.94) CYP2D6SLC6A4KCNH2LMNACYP1A2
Ambroxol SCHEMBL11533052 0.93 CYP2D6 (0.87) CYP2D6SLC6A4KCNH2LMNACYP1A2
SCHEMBL24446418 0.92 CYP2D6 (0.84) CYP2D6SLC6A4KCNH2LMNACYP1A2
SCHEMBL22927201 0.92 CYP2D6 (0.84) CYP2D6SLC6A4KCNH2LMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 527 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120152742-A Polymer with dual therapeutic agents 索尼集团公司 2025-06-13 — — CN claimed
EP-3538083-B1 FORMULATIONS FOR THE TREATMENT OF OCULAR SURFACE DISEASES AND RELATED METHODS NEUVISION DEV LLC (US) 2024-07-10 — — EP claimed
CN-118159296-A Automatic synthesis of polymeric double drugs 索尼集团公司 2024-06-07 — — CN claimed
CN-117637184-B Bayesian sensitivity analysis method and system for longitudinal data 湖北省疾病预防控制中心(湖北省预防医学科学院) 2024-06-04 — — CN claimed
CN-118021768-A Ambroxol oral-dissolving film composition, preparation method and application thereof 上海云晟研新生物科技有限公司 2024-05-14 — — CN claimed
CN-117637184-A Bayesian sensitivity analysis method and system for longitudinal data 湖北省疾病预防控制中心(湖北省预防医学科学院) 2024-03-01 — — CN claimed
US-11823381-B2 Knowledge distillation with adaptive asymmetric label sharpening for semi-supervised fracture detection in chest x-rays PING AN TECHNOLOGY (SHENZHEN) CO., LTD. (CN) 2023-11-21 — — US claimed
CN-116762105-A Knowledge distillation with adaptive asymmetric marker sharpening for semi-supervised fracture detection in chest radiography 平安科技(深圳)有限公司 2023-09-15 — — CN claimed
CN-113444001-B Ambroxol hydrochloride production process 江西荣兴药业有限公司 2023-09-08 — — CN claimed
CN-115707459-A Synergistic composition of drug-resistant tumor treatment drugs 复旦大学 2023-02-21 — — CN claimed
EP-0586738-A1 Enhanced chemotherapeutic compositions against microbial infections in fish containing a benzylamine derivative and an antimicrobial substance BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 1994-03-16 — — EP claimed
EP-0587135-A1 Enhanced chemotherapeutic compositions against microbial infections in fish contaning a benzylamine derivative and an antimicrobial substance BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 1994-03-16 — — EP claimed
EP-0138020-B1 ANTI-ADHESIVE PROPHYLACTICA AND MEDICINES CONTAINING A SECRETOLYTICALLY ACTIVE BENZYLAMINE DERIVATIVE Dr. Karl Thomae GmbH (DE) 1992-06-03 — — EP claimed
EP-0240907-B1 Use of trans-4-[(2-amino-3,5-dibromobenzyl)amino]cyclohexanol KREWEL-WERKE GMBH (DE) 1991-05-29 — — EP claimed
EP-0150787-B1 COMPOUND HAVING ANTIBRONCHOPNEUMOPATHIC ACTIVITY, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT PULITZER ITALIANA S.p.A. (IT) 1988-04-27 — — EP claimed
EP-0240907-A2 Use of trans-4-[(2-amino-3,5-dibromobenzyl)amino]cyclohexanol KREWEL-WERKE GMBH (DE) 1987-10-14 — — EP claimed
EP-0088943-B1 COMPOSITION FOR THE RESORPTION OF INJECTED ANTIBACTERIAL SUBSTANCES AND MIXTURES CONTAINING A BENZYL AMINE DERIVATIVE BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 1986-08-13 — — EP claimed
EP-0138020-A2 Anti-adhesive prophylactica and medicines containing a secretolytically active benzylamine derivative Dr. Karl Thomae GmbH (DE) 1985-04-24 — — EP claimed
EP-0088943-A2 Composition for the resorption of injected antibacterial substances and mixtures containing a benzyl amine derivative BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 1983-09-21 — — EP claimed
US-3993778-A ORALLY ADMINISTERING BOEHRINGER INGELHEIM GMBH (DT) 1976-11-23 — — US claimed
Send feedback