Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ACACA | Q13085 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | EPOR | P19235 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27108628 | 0.87 | LTA4H (0.51) | SMN1; SMN2LTA4HALOX5MAOBFFAR1 | |
| SCHEMBL12703229 | 0.87 | YAP1 (0.46) | KMT2ASMN1; SMN2ACACALTA4HMEN1 | |
| SCHEMBL1592985 | 0.83 | PSEN1 (0.46) | KMT2ASMN1; SMN2ACACALTA4HMEN1 | |
| SCHEMBL7804061 | 0.83 | CACNA1B (0.47) | ACACAALOX5SMPD1PTGES | |
| SCHEMBL2646779 | 0.83 | LTA4H (0.49) | KMT2ASMN1; SMN2LTA4HALOX5MAOB | |
| SCHEMBL2846665 | 0.81 | KMT2A (0.56) | KMT2ASMN1; SMN2LTA4HALOX5MEN1 | |
| SCHEMBL22394806 | 0.81 | KMT2A (0.51) | KMT2AMEN1 | |
| SCHEMBL2842744 | 0.80 | OPRD1 (0.48) | KMT2AMEN1 | |
| SCHEMBL2646847 | 0.80 | POLB (0.54) | KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL9019941 | 0.79 | KMT2A (0.59) | KMT2ASMN1; SMN2LTA4HALOX5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138901-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS, DERIVATIVES THEREOF, AND RELATED METHODS OF USE | BIOGEN IDEC MA INC (US) | 2010-12-02 | — | — | WO | disclosed |