SCHEMBL28474141

SCHEMBL28474141

c1ccc2c3c4c(cc5ccccc5c4cc2c1)CC3

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
CYP1A2 P05177 3/20 0.46
ACHE P22303 3/20 0.46
FYN P06241 2/20 0.46
AHR P35869 2/20 0.46
LCK P06239 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
MAPT P10636 1/20 0.46
SLC6A2 P23975 1/20 0.46
HSD17B10 Q99714 4/20 0.45
HIF1A Q16665 2/20 0.45
CYP1B1 Q16678 1/20 0.45
TSHR P16473 2/20 0.37
HPGD P15428 2/20 0.37
ERBB2 P04626 1/20 0.37
MAOA P21397 1/20 0.37
MAPK1 P28482 1/20 0.37
CASP1 P29466 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TRPM4 Q8TD43 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8955 0.77 CYP1A2 (0.46) ALDH1A1CYP1A2ACHEFYNAHR
SCHEMBL12753 0.76 ALDH1A1 (0.48) ALDH1A1CYP1A2ACHEFYNAHR
SCHEMBL29765599 0.76 ALDH1A1 (0.48) ALDH1A1CYP1A2ACHEFYNAHR
Acenaphthene SCHEMBL28870353 0.74 CYP1A2 (0.47) ALDH1A1CYP1A2ACHEFYNAHR
Cholanthrene SCHEMBL9048 0.72 ALDH1A1 (0.65) ALDH1A1CYP1A2ACHEFYNAHR
SCHEMBL28783299 0.71 CYP1A2 (0.62) ALDH1A1CYP1A2ACHEFYNAHR
SCHEMBL9347612 0.71 CYP1A2 (0.55) ALDH1A1CYP1A2ACHEFYNAHR
SCHEMBL14875126 0.71 PTPN22 (0.42) ALDH1A1CYP1A2ACHEFYNAHR
SCHEMBL2321840 0.69 ALDH1A1 (0.62) ALDH1A1CYP1A2ACHEFYNAHR
SCHEMBL4846372 0.69 ALDH1A1 (0.62) ALDH1A1CYP1A2ACHEFYNAHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109384636-B Hydrocarbon fuel-rich propellant and preparation method thereof 湖北航天化学技术研究所 2020-09-22 CN claimed