SCHEMBL8955

SCHEMBL8955

c1ccc2c3c4c(cccc4cc2c1)CC3

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.46
FYN P06241 2/20 0.46
ACHE P22303 2/20 0.46
AHR P35869 2/20 0.46
ERBB2 P04626 1/20 0.46
MAOA P21397 1/20 0.46
ALDH1A1 P00352 9/20 0.42
MAPT P10636 2/20 0.42
LCK P06239 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
SLC6A2 P23975 1/20 0.42
HPGD P15428 7/20 0.41
KDM4E B2RXH2 3/20 0.41
MEN1 O00255 2/20 0.41
GAA P10253 2/20 0.41
KMT2A Q03164 2/20 0.41
LMNA P02545 2/20 0.41
CYP11B1 P15538 1/20 0.40
CYP11B2 P19099 1/20 0.40
CES1 P23141 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acenaphthene SCHEMBL28870353 0.96 CYP1A2 (0.47) CYP1A2FYNACHEAHRERBB2
Benzoquinone SCHEMBL1280497 0.90 CES1 (0.41) CYP1A2FYNACHEAHRERBB2
Cholanthrene SCHEMBL9048 0.82 ALDH1A1 (0.65) CYP1A2FYNACHEAHRERBB2
SCHEMBL28474141 0.77 ALDH1A1 (0.46) CYP1A2FYNACHEAHRERBB2
SCHEMBL14158431 0.77 KDM4E (0.46) CYP1A2FYNACHEAHRERBB2
SCHEMBL8754072 0.77 CYP1A2 (0.42) CYP1A2FYNACHEAHRERBB2
Benzo[Def]Chrysene SCHEMBL1557634 0.77 CYP1A2 (0.76) CYP1A2FYNACHEAHRERBB2
SCHEMBL12753 0.76 ALDH1A1 (0.48) CYP1A2FYNACHEAHRERBB2
SCHEMBL29765599 0.76 ALDH1A1 (0.48) CYP1A2FYNACHEAHRERBB2
SCHEMBL11681631 0.75 ALDH1A1 (0.43) CYP1A2FYNACHEAHRERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1083 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110226241-B Organic electroluminescent element and electronic device 出光兴产株式会社 2022-08-30 CN claimed
CN-108344831-A Method for measuring polycyclic aromatic hydrocarbon in tobacco, main stream smoke or heated non-burning cigarette 国家烟草质量监督检验中心 2018-07-31 CN claimed
CN-103923065-A Terpyridine derivative and application thereof in white organic light-emitting diode CHINESE ACAD TECH INST PHYSICS 2014-07-16 CN claimed
CN-103896973-A Di (trimethyl phenyl) boron derivative and application thereof in white organic electroluminescent diode CHINESE ACAD TECH INST PHYSICS 2014-07-02 CN claimed
CN-102102015-B Coumarin derivative organic electroluminescent material and preparation method and application thereof CHINESE ACAD TECH INST PHYSICS 2013-12-18 CN claimed
CN-103435597-A 1,3, 5-triazine derivative and application thereof in white organic electroluminescent diode CHINESE ACAD TECH INST PHYSICS 2013-12-11 CN claimed
CN-102260257-A Pyrazolo [3,4-b ] pyridine derivative and application thereof in white organic electroluminescent device 2011-11-30 CN claimed
CN-102101852-A Coumarin derivative, preparation method thereof and application thereof in white light organic electroluminescent device CHINESE ACAD TECH INST PHYSICS 2011-06-22 CN claimed
CN-102102015-A Coumarin derivative organic electroluminescent material and preparation method and application thereof CHINESE ACAD TECH INST PHYSICS 2011-06-22 CN claimed
CN-102070632-A Pyridoimidazole derivative and application thereof in organic electroluminescent device CHINESE ACAD TECH INST PHYSICS 2011-05-25 CN claimed
EP-0983222-B1 PHARMACEUTICAL AGENTS FOR THE TREATMENT OF CEREBRAL AMYLOIDOSIS NYMOX CORP (CA) 2007-11-28 EP claimed
US-6358633-B1 ORGANIC AROMATIC COMPOUNDS AS DOPES FOR EMITTER LAYERS, HOLE INJECTION ELECTRODES SANYO ELECTRIC CO., LTD. (JP) 2002-03-19 US claimed
EP-1020510-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT Sanyo Electric Co., Ltd. (JP) 2000-07-19 EP claimed
US-4791232-A ANTITUMOR AGENTS BURROUGHS WELLCOME CO. (US) 1988-12-13 US claimed
US-20250340519-A1 RADIOLABELLED COMPOUND OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2025-11-06 US disclosed
US-12448555-B2 Composition for forming thermally conductive material, thermally conductive material, and surface-modified inorganic substance FUJIFILM CORPORATION (JP) 2025-10-21 US disclosed
EP-4624459-A2 RADIOLABELLED COMPOUND Oxford University Innovation Limited (GB) 2025-10-01 EP disclosed
US-4248976-A COMPRISING A PHOSPHORUS COMPOUND AND AN AROMATIC COMPOUND CIBA-GEIGY AG (CH) 1981-02-03 US disclosed
US-4172858-A Flame-resistant polymer compositions CIBA-GEIGY AG (CH) 1979-10-30 US disclosed
US-4163731-A HYDRAULIC FLUIDS CIBA-GEIGY AG (CH) 1979-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250340519-A1 RADIOLABELLED COMPOUND PARP3, PARP2, PARP1 CYP1A2 1388/4885FYN 2339/4885ACHE 4142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.