Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 8/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PRKACA | P17612 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CDK7 | P50613 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | PRKX | P51817 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.37 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.37 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL632053 | 0.79 | ASIC3 (0.59) | KMOCDC7DAPK3MAP4K4PIM1 | |
| SCHEMBL29392239 | 0.79 | ASIC3 (0.59) | KMOCDC7DAPK3MAP4K4PIM1 | |
| SCHEMBL1257940 | 0.79 | KMO (0.58) | KMOCDC7DAPK3MAP4K4PIM1 | |
| SCHEMBL714571 | 0.78 | ASIC3 (0.57) | KMOMIFASIC3GRM5NPC1 | |
| SCHEMBL3826204 | 0.78 | ABL1 (0.44) | KMOCDC7DAPK3MAP4K4PIM1 | |
| SCHEMBL712321 | 0.76 | MIF (0.37) | KMOCLK4MIFASIC3AAK1 | |
| SCHEMBL19244911 | 0.76 | KMO (0.46) | KMOCDC7DAPK3MAP4K4PIM1 | |
| SCHEMBL3406220 | 0.76 | KMO (0.46) | KMOCDC7DAPK3MAP4K4PIM1 | |
| SCHEMBL2907264 | 0.76 | CYP1A2 (0.44) | KMOCDC7DAPK3MAP4K4PIM1 | |
| SCHEMBL15339601 | 0.76 | KDM4E (0.46) | KMOCDC7DAPK3MAP4K4PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349949-B | N-substituted indole derivatives as PGE2 receptor modulators | 爱杜西亚药品有限公司 | 2020-11-17 | — | — | CN | disclosed |
| CN-108349949-A | N- substituted indole derivatives as PGE2 receptor modulators | 爱杜西亚药品有限公司 | 2018-07-31 | — | — | CN | disclosed |