Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.59 |
| ▸ | MIF | P14174 | 1/20 | 0.59 |
| ▸ | KMO | O15229 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMO | Q99835 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29392239 | 1.00 | ASIC3 (0.59) | ASIC3MIFKMOSMN1; SMN2NPC1 | |
| SCHEMBL20137316 | 0.96 | ASIC3 (0.55) | ASIC3MIFKMOSMN1; SMN2NPC1 | |
| SCHEMBL16659314 | 0.87 | KMO (0.57) | ASIC3MIFKMOSMN1; SMN2NPC1 | |
| Phenylboronic Acid SCHEMBL5325420 | 0.86 | KMO (0.46) | ASIC3MIFKMOSMN1; SMN2NPC1 | |
| SCHEMBL284286 | 0.84 | ASIC3 (0.71) | ASIC3MIFKMOSMN1; SMN2NPC1 | |
| SCHEMBL1257940 | 0.83 | KMO (0.58) | ASIC3MIFKMOSMN1; SMN2NPC1 | |
| SCHEMBL2228047 | 0.82 | KMO (0.61) | KMOCDC7DAPK3MAP4K4PIM1 | |
| SCHEMBL30459860 | 0.82 | KMO (0.61) | KMOCDC7DAPK3MAP4K4PIM1 | |
| SCHEMBL29406194 | 0.81 | ASIC3 (0.68) | ASIC3MIFKMOSMN1; SMN2NPC1 | |
| SCHEMBL27904874 | 0.81 | ASIC3 (0.68) | ASIC3MIFKMOSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1796673-A2 | NOVEL PYRIMIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | Reddy US Therapeutics, Inc. (US) | 2007-06-20 | — | — | EP | claimed |
| US-20060084645-A1 | Novel pyrimidine compounds, process for their preparation and compositions containing them | DR. REDDY'S LABORATORIES LTD. (IN) | 2006-04-20 | — | — | US | claimed |
| WO-2006034473-A2 | NOVEL PYRIMIDINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | REDDY US THERAPEUTICS, INC. (US) | 2006-03-30 | — | — | WO | claimed |
| US-20260049243-A1 | Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Equipment, Lighting Device, and Electronic Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2026-02-19 | — | — | US | disclosed |
| US-12460130-B2 | Organic compound, light-emitting device, light-emitting apparatus, electronic equipment, lighting device, and electronic device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2025-11-04 | — | — | US | disclosed |
| US-12400590-B2 | Light-emitting element, light-emitting device, electronic device, and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2025-08-26 | — | — | US | disclosed |
| US-12390463-B2 | Dosage forms and regimens for amino acid compounds | PLIANT THERAPEUTICS, INC. (US) | 2025-08-19 | — | — | US | disclosed |
| US-20250223288-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS, INC. | 2025-07-10 | — | — | US | disclosed |
| CN-115867280-B | 5-Amino-8- (4-pyridyl) - [1,2,4] triazolo [4,3-C ] pyrimidin-3-one compounds for anticancer use | 奈克斯拉制药英国有限公司 | 2025-05-27 | — | — | CN | disclosed |
| EP-4520329-A2 | TREATMENT OF RESPIRATORY DISEASES WITH AMINO ACID COMPOUNDS | Pliant Therapeutics, Inc. (US) | 2025-03-12 | — | — | EP | disclosed |
| EP-4509512-A2 | AMINO ACID COMPOUNDS AND METHODS OF USE | Pliant Therapeutics, Inc. (US) | 2025-02-19 | — | — | EP | disclosed |
| US-6613773-B2 | Pyrimidinyloxyphenyl-3-alkoxypropenoates derivatives | SYNGENTA LIMITED (GB) | 2003-09-02 | — | — | US | disclosed |
| US-20030060626-A1 | Fungicides | SYNGENTA LIMITED (GB) | 2003-03-27 | — | — | US | disclosed |
| WO-2002024663-A2 | PYRIMIDINE COMPOUNDS AND THEIR USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-03-28 | — | — | WO | disclosed |
| WO-2001087845-A2 | N-CONTAINING HETEROCYCLIC COMPOUNDS AND THEIR USE AS 5-HT ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-22 | — | — | WO | disclosed |
| CN-1036519-C | Fungicides | ICI PLC (GB) | 1997-11-26 | — | — | CN | disclosed |
| EP-0468695-B1 | Fungicides | ZENECA LTD (GB) | 1996-09-11 | — | — | EP | disclosed |
| CN-1060289-A | Mycocide | ICI PLC (GB) | 1992-04-15 | — | — | CN | disclosed |
| EP-0468695-A1 | Fungicides | ZENECA LIMITED (GB) | 1992-01-29 | — | — | EP | disclosed |
| US-3950525-A | BRONCHODILATION, 4-HYDROXY-6-ARYL PYRIMIDINES | PFIZER INC. (US) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060084645-A1 | Novel pyrimidine compounds, process for their preparation and compositions containing them | UMPS, DPYD, TYMS | ASIC3 4547/4885MIF 3444/4885KMO 3306/4885 |
| US-12460130-B2 | Organic compound, light-emitting device, light-emitting apparatus, electronic equipment, lighting device, and electronic device | SLCO4C1, SLCO2A1, SLCO2B1 | ASIC3 2603/4885MIF 244/4885KMO 2826/4885 |
| US-20030060626-A1 | Fungicides | CYP51A1, CYP1A1, CYP1A2 | ASIC3 2231/4885MIF 3360/4885KMO 215/4885 |
| US-12390463-B2 | Dosage forms and regimens for amino acid compounds | ITGB6, ITGA6, ITGAV | ASIC3 2058/4885MIF 1064/4885KMO 4588/4885 |
| US-20250223288-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | ITGB6, ITGA6, ITGA5 | ASIC3 820/4885MIF 971/4885KMO 4450/4885 |
| US-20260049243-A1 | Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Equipment, Lighting Device, and Electronic Device | CRY1, INTS9, STRA6 | ASIC3 1786/4885MIF 132/4885KMO 2685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.