Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2865800 | 0.88 | KMT2A (0.56) | KMT2AALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL6676537 | 0.87 | KMT2A (0.71) | KMT2AALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL2846389 | 0.85 | KMT2A (0.54) | KMT2AALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL6673419 | 0.82 | BCHE (0.61) | KMT2AALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL11063684 | 0.79 | TTR (0.66) | TTRKMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL27446847 | 0.79 | HPGD (0.66) | ALDH1A1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL3427560 | 0.78 | GAA (0.60) | KMT2AALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL29828592 | 0.77 | PTPN7 (0.58) | KMT2A | |
| SCHEMBL2846850 | 0.77 | PTPN7 (0.58) | KMT2A | |
| SCHEMBL8429041 | 0.77 | TTR (0.71) | TTRKMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099316-B1 | FLAVOUR MODULATING DERIVATIVE OF A CARBOXYLIC ACID AND A PURINE, PYRIMIDINE, NUCLEOSIDE OR NUCLEOTIDE | GIVAUDAN SA (CH) | 2017-06-21 | — | — | EP | disclosed |
| US-20130028846-A1 | Flavour Modulating Derivative of a Carboxylic Acid and a Purine, Pyrimidine, Nucleoside, or Nucleotide | GIVAUDAN NEDERLAND SERVICES B.V. (NL) | 2013-01-31 | — | — | US | disclosed |
| US-8293215-B2 | Flavour modulating derivative of a carboxylic acid and a purine, pyrimidine, nucleoside, or nucleotide | GIVAUDAN NEDERLAND SERVICES B.V. (NL) | 2012-10-23 | — | — | US | disclosed |
| US-20100129515-A1 | FLAVOUR MODULATING SUBSTANCES | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2010-05-27 | — | — | US | disclosed |
| US-20100074850-A1 | Flavour Modulating Derivative of a Carboxylic Acid and a Purine, Pyrimidine, Nucleoside, or Nucleotide | GIVAUDAN NEDERLAND SERVICES B.V. (NL) | 2010-03-25 | — | — | US | disclosed |
| EP-2099316-A1 | FLAVOUR MODULATING DERIVATIVE OF A CARBOXYLIC ACID AND A PURINE, PYRIMIDINE, NUCLEOSIDE OR NUCLEOTIDE | Givaudan Nederland Services B.V. (NL) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008072963-A1 | FLAVOUR MODULATING DERIVATIVE OF A CARBOXYLIC ACID AND A PURINE, PYRIMIDINE, NUCLEOSIDE OR NUCLEOTIDE | GIVAUDAN NEDERLAND SERVICES B.V. (NL) | 2008-06-19 | — | — | WO | disclosed |
| EP-1915063-A2 | N-VANILLYL UREA DERIVATIVES AS FLAVOUR MODULATING SUBSTANCES | Quest International Services B.V. (NL) | 2008-04-30 | — | — | EP | disclosed |
| WO-2007013811-A2 | N-VANILLYL UREA DERIVATIVES AS FLAVOUR MODULATING SUBSTANCES | QUEST INTERNATIONAL SERVICES B.V. (NL) | 2007-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100074850-A1 | Flavour Modulating Derivative of a Carboxylic Acid and a Purine, Pyrimidine, Nucleoside, or Nucleotide | NUDT1, GART, UMPS | TTR 1526/4885KMT2A 3853/4885ALDH1A1 183/4885 |
| US-20130028846-A1 | Flavour Modulating Derivative of a Carboxylic Acid and a Purine, Pyrimidine, Nucleoside, or Nucleotide | NUDT1, GART, UMPS | TTR 1482/4885KMT2A 3846/4885ALDH1A1 211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.