Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | TPMT | P51580 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8128858 | 0.89 | HTT (0.54) | HTTLMNAMAPK1RAB9AALDH1A1 | |
| SCHEMBL4630412 | 0.87 | LMNA (0.48) | HTTLMNAMAPK1RAB9AALDH1A1 | |
| SCHEMBL18010707 | 0.85 | TSHR (0.47) | HTTLMNAMAPK1RAB9AALDH1A1 | |
| SCHEMBL23464217 | 0.85 | PARP10 (0.50) | HTTLMNAMAPK1RAB9AALDH1A1 | |
| SCHEMBL14855948 | 0.83 | CA12 (0.61) | HTTLMNAMAPK1RAB9AALDH1A1 | |
| SCHEMBL22394631 | 0.83 | TSHR (0.48) | HTTLMNAMAPK1RAB9AALDH1A1 | |
| SCHEMBL201405 | 0.77 | LMNA (0.53) | HTTLMNAMAPK1RAB9AALDH1A1 | |
| SCHEMBL29792549 | 0.77 | LMNA (0.53) | HTTLMNAMAPK1RAB9AALDH1A1 | |
| SCHEMBL14857211 | 0.76 | CA9 (0.50) | HTTLMNAMAPK1RAB9AALDH1A1 | |
| SCHEMBL20157863 | 0.76 | ALDH1A1 (0.50) | HTTLMNAMAPK1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111801322-A | Kinase inhibitors for the treatment of central and peripheral nervous system disorders | 迈阿密大学 | 2020-10-20 | — | — | CN | disclosed |