Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | RAB9A | P51151 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 6/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2705048 | 0.84 | RAB9A (0.60) | SMN1; SMN2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL21812776 | 0.84 | RAB9A (0.66) | SMN1; SMN2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL202654 | 0.84 | MEN1 (0.60) | SMN1; SMN2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL2225692 | 0.84 | RAB9A (0.58) | SMN1; SMN2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL6822229 | 0.84 | RAB9A (0.67) | SMN1; SMN2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL16181394 | 0.84 | LOXL2 (0.51) | SMN1; SMN2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL15348483 | 0.83 | LOXL2 (0.64) | SMN1; SMN2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL202106 | 0.80 | GAA (0.59) | SMN1; SMN2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL204739 | 0.80 | L3MBTL1 (0.56) | SMN1; SMN2MAPTRAB9AMEN1KMT2A | |
| SCHEMBL2226336 | 0.80 | MAPT (0.57) | SMN1; SMN2MAPTRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909109-A | 4- (4-halogenated phenyl) -2- (substituted styryl) thiazole compound and application thereof | 浙江工业大学 | 2020-11-10 | — | — | CN | disclosed |