Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LPO | P22079 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28478509 | 0.88 | MAPT (0.60) | ALDH1A1MAPTTP53LMNALPO | |
| SCHEMBL1609235 | 0.88 | ALDH1A1 (0.60) | ALDH1A1MAPTTP53LMNANPC1 | |
| SCHEMBL28480628 | 0.82 | ALDH1A1 (0.62) | ALDH1A1LMNANPC1RAB9ACYP1A2 | |
| SCHEMBL28480613 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTTP53LMNANPC1 | |
| SCHEMBL18001863 | 0.76 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9AHDAC3HDAC4 | |
| SCHEMBL28539417 | 0.76 | ALDH1A1 (0.58) | ALDH1A1MAPTTP53LMNANPC1 | |
| SCHEMBL28469317 | 0.76 | MAPT (0.55) | ALDH1A1MAPTTP53LMNANPC1 | |
| SCHEMBL1244152 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNARAB9AL3MBTL1 | |
| SCHEMBL28475115 | 0.74 | MAPT (0.55) | ALDH1A1MAPTTP53LMNAHDAC8 | |
| SCHEMBL9400665 | 0.74 | VEGFA (0.56) | ALDH1A1MAPTTP53LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358923-B | Sophoridine pyrrole and indole derivatives, and preparation method and application thereof | 广西大学 | 2020-11-03 | — | — | CN | claimed |
| CN-108047226-B | Matrine pyrrole and indole derivatives, and preparation method and application thereof | 广西大学 | 2020-11-03 | — | — | CN | claimed |