Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | RBP4 | P02753 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | AHR | P35869 | 3/20 | 0.55 |
| ▸ | FLT3 | P36888 | 6/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21855639 | 0.88 | FLT3 (0.65) | ALDH1A1MAPTRBP4LMNATSHR | |
| SCHEMBL6114106 | 0.87 | FLT3 (0.67) | ALDH1A1MAPTRBP4LMNATSHR | |
| SCHEMBL13779981 | 0.84 | FLT3 (0.69) | ALDH1A1MAPTRBP4LMNATSHR | |
| SCHEMBL29806029 | 0.84 | FLT3 (0.69) | ALDH1A1MAPTRBP4LMNATSHR | |
| SCHEMBL20181949 | 0.84 | FLT3 (0.69) | ALDH1A1MAPTRBP4LMNATSHR | |
| SCHEMBL29335972 | 0.81 | DRD2 (0.63) | ALDH1A1MAPTRBP4LMNATSHR | |
| SCHEMBL29336193 | 0.81 | ALDH1A1 (0.59) | ALDH1A1MAPTRBP4LMNATSHR | |
| SCHEMBL30589612 | 0.80 | ALDH1A1 (0.64) | ALDH1A1MAPTRBP4LMNATSHR | |
| SCHEMBL15253698 | 0.80 | ALDH1A1 (0.64) | ALDH1A1MAPTRBP4LMNATSHR | |
| SCHEMBL23244263 | 0.79 | ALDH1A1 (0.77) | ALDH1A1MAPTRBP4LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112370452-A | Heterocyclic amides as kinase inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-02-19 | — | — | CN | disclosed |
| CN-107624111-B | Heterocyclic amides as kinase inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2020-11-03 | — | — | CN | disclosed |