Sugi Predict

Sugi Predict / Compounds / SCHEMBL22894331

SCHEMBL22894331

SCHEMBL22894331

c1cc(Oc2cc(Oc3cccc(-n4c5ccccc5c5cc(-n6c7ccccc7c7ccccc76)ccc54)c3)cc(-n3c4ccccc4c4ccccc43)c2)cc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.47
▸ L3MBTL1 Q9Y468 2/20 0.47
▸ ATM Q13315 1/20 0.47
▸ PPARG P37231 7/20 0.39
▸ MEN1 O00255 2/20 0.37
▸ ALDH1A1 P00352 2/20 0.37
▸ MAPT P10636 2/20 0.37
▸ KMT2A Q03164 2/20 0.37
▸ HPGD P15428 1/20 0.37
▸ HTT P42858 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ NR1H2 P55055 2/20 0.37
▸ NR1H3 Q13133 2/20 0.37
▸ PPARA Q07869 2/20 0.37
▸ NTRK1 P04629 1/20 0.35
▸ IGF1R P08069 1/20 0.35
▸ FGFR1 P11362 1/20 0.35
▸ NTRK2 Q16620 1/20 0.35
▸ PTPN1 P18031 1/20 0.35
▸ REN P00797 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31497265 1.00 KDM4E (0.47) KDM4EL3MBTL1ATMPPARGMEN1
SCHEMBL26464409 0.91 KDM4E (0.42) KDM4EL3MBTL1ATMPPARGMEN1
SCHEMBL16890333 0.90 KDM4E (0.57) KDM4EL3MBTL1ATMPPARGMEN1
SCHEMBL14649186 0.86 KDM4E (0.55) KDM4EL3MBTL1ATMPPARGMEN1
SCHEMBL28477376 0.85 KDM4E (0.61) KDM4EL3MBTL1ATMPPARGNR1H2
SCHEMBL32661512 0.84 KDM4E (0.47) KDM4EL3MBTL1ATMPPARGMEN1
SCHEMBL26464393 0.84 KDM4E (0.47) KDM4EL3MBTL1ATMPPARGMEN1
SCHEMBL31497262 0.84 KDM4E (0.41) KDM4EL3MBTL1ATMPPARGMEN1
SCHEMBL22894369 0.84 KDM4E (0.41) KDM4EL3MBTL1ATMPPARGMEN1
SCHEMBL16890212 0.83 KDM4E (0.53) KDM4EL3MBTL1ATMPPARGMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230130170-A1 LIGHT EMITTING DEVICE AND FUSED POLYCYCLIC COMPOUND FOR LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-04-27 — — US disclosed
US-20230130170-A1 LIGHT EMITTING DEVICE AND FUSED POLYCYCLIC COMPOUND FOR LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-04-27 — — US disclosed
US-20210013423-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND FUSED POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-01-14 — — US disclosed
CN-112194672-A Organic electroluminescent device and condensed polycyclic compound 三星显示有限公司 2021-01-08 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230130170-A1 LIGHT EMITTING DEVICE AND FUSED POLYCYCLIC COMPOUND FOR LIGHT EMITTING DEVICE LEF1, NFE2L2, CACNA2D1 KDM4E 2826/4885L3MBTL1 257/4885ATM 4415/4885
US-20210013423-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND FUSED POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE ODC1, PIEZO1, LEF1 KDM4E 1832/4885L3MBTL1 551/4885ATM 3920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.