Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131869 | 0.89 | — | — | |
| SCHEMBL13925528 | 0.89 | — | — | |
| Ammonia Solution, Strong SCHEMBL143304 | 0.87 | LMNA (0.70) | LMNAL3MBTL1TAAR1ALDH1A1GAA | |
| SCHEMBL12603779 | 0.82 | L3MBTL1 (0.64) | LMNAL3MBTL1TAAR1ALDH1A1GAA | |
| SCHEMBL18721350 | 0.82 | LMNA (0.64) | LMNAL3MBTL1TAAR1ALDH1A1GAA | |
| SCHEMBL145807 | 0.82 | LMNA (0.64) | LMNAL3MBTL1TAAR1ALDH1A1GAA | |
| Formaldehyde SCHEMBL28062945 | 0.82 | LMNA (0.64) | LMNAL3MBTL1TAAR1ALDH1A1GAA | |
| SCHEMBL28348764 | 0.80 | LMNA (0.61) | LMNAL3MBTL1TAAR1ALDH1A1GAA | |
| SCHEMBL12736546 | 0.79 | LMNA (0.55) | LMNAL3MBTL1ALDH1A1GAAIDO1 | |
| SCHEMBL27398280 | 0.78 | LMNA (0.59) | LMNAL3MBTL1TAAR1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111943886-B | Substituted pyridine compound and preparation method thereof | 华中师范大学 | 2022-02-08 | — | — | CN | disclosed |
| CN-111943886-A | Substituted pyridine compound and preparation method thereof | 华中师范大学 | 2020-11-17 | — | — | CN | disclosed |