SCHEMBL145807

SCHEMBL145807

CCc1ccc(-c2ccc(F)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.64
L3MBTL1 Q9Y468 1/20 0.53
MAOB P27338 1/20 0.52
GCGR P47871 1/20 0.46
MAPK14 Q16539 1/20 0.46
IDO1 P14902 1/20 0.46
LOXL2 Q9Y4K0 1/20 0.46
ALDH1A1 P00352 2/20 0.46
GAA P10253 1/20 0.46
PYCR1 P32322 1/20 0.46
TP53 P04637 1/20 0.43
EGFR P00533 1/20 0.43
TAAR1 Q96RJ0 4/20 0.43
ADCY1 Q08828 1/20 0.43
MEN1 O00255 1/20 0.43
MAPT P10636 1/20 0.43
KMT2A Q03164 1/20 0.43
FAAH O00519 1/20 0.42
UCHL1 P09936 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8990848 0.93 L3MBTL1 (0.58) LMNAL3MBTL1MAOBGCGRMAPK14
SCHEMBL13925528 0.92
SCHEMBL131869 0.92
Ammonia Solution, Strong SCHEMBL143304 0.89 LMNA (0.70) LMNAL3MBTL1IDO1LOXL2ALDH1A1
SCHEMBL1702558 0.86 TP53 (0.56) L3MBTL1ALDH1A1TP53EGFRTAAR1
SCHEMBL2776957 0.86 TP53 (0.56) L3MBTL1ALDH1A1TP53EGFRTAAR1
SCHEMBL18721350 0.84 LMNA (0.64) LMNAL3MBTL1IDO1LOXL2ALDH1A1
SCHEMBL12603779 0.84 L3MBTL1 (0.64) LMNAL3MBTL1MAOBIDO1LOXL2
SCHEMBL13282199 0.83 CYP17A1 (0.47) LMNAL3MBTL1MAOBGCGRMAPK14
SCHEMBL19300894 0.83 RXRA (0.50) LMNAL3MBTL1MAOBGCGRMAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2532663-B1 Naphthalenetetracarboxylic acid derivatives and their use as semiconductors BASF SE (DE) 2016-03-16 EP claimed
EP-2532663-A1 Naphthalenecarboxylic acid derivatives and their use as semiconductors BASF SE (DE) 2012-12-12 EP claimed
US-20230212121-A1 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS TRINEURO (KR) 2023-07-06 US disclosed
US-11230571-B2 Anthelmintic depsipeptide compounds Boehringer Ingelheim Animal Health USA Inc. (US) 2022-01-25 US disclosed
EP-3331965-B1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2022-01-05 EP disclosed
EP-3922639-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS Boehringer Ingelheim Animal Health USA Inc. (US) 2021-12-15 EP disclosed
US-20190248840-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS Boehringer Ingelheim Animal Health USA Inc. (US) 2019-08-15 US disclosed
US-20190031624-A1 THERAPEUTIC COMPOUNDS AND METHODS TO TREAT INFECTION UNIV RUTGERS (US) 2019-01-31 US disclosed
US-20180223187-A1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2018-08-09 US disclosed
US-20180223187-A1 LIQUID CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2018-08-09 US disclosed
US-20180142154-A1 LIQUID CRYSTAL COMPOSITION HAVING GOOD PHOTOSTABILITY AND THERMOSTABILITY, AND LIQUID CRYSTAL DISPLAY ELEMENT JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2018-05-24 US disclosed
US-20080303002-A1 DISPLAY MATERIAL AND AUTOMOBILE MEMBER FUJIFILM CORPORATION (JP) 2008-12-11 US disclosed
US-20080300405-A1 Naphthalenetetracarboxylic Aicd Derivatives and their Use as Semiconductors BASF SE (DE) 2008-12-04 US disclosed
EP-1966206-A1 NAPHTHALENETETRACARBOXYLIC ACID DERIVATIVES AND THEIR USE AS SEMICONDUCTORS BASF SE (DE) 2008-09-10 EP disclosed
WO-2007074137-A1 NAPHTHALENETETRACARBOXYLIC ACID DERIVATIVES AND THEIR USE AS SEMICONDUCTORS BASF SE (DE) 2007-07-05 WO disclosed
US-20070117797-A1 Alkylamino, arylamino, and sulfonamido cyclopentyl amide modulators of chemokine receptor activity MERCK SHARP & DOHME CORP. 2007-05-24 US disclosed
US-4027041-A Ethyl- and vinylbenzenes as antithrombotic agents ELI LILLY AND COMPANY (US) 1977-05-31 US disclosed
US-4024284-A Ethyl- and vinylbenzenes as anti-inflammatory agents ELI LILLY AND COMPANY (US) 1977-05-17 US disclosed
US-3975542-A Ethyl- and vinylbenzenes as antithromobiotic agents ELI LILLY AND COMPANY (US) 1976-08-17 US disclosed
US-3975543-A Ethyl- and vinylbenzenes as anti-inflammatory agents ELI LILLY AND COMPANY (US) 1976-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190031624-A1 THERAPEUTIC COMPOUNDS AND METHODS TO TREAT INFECTION ABCB11, SLC10A1, SLC47A1 LMNA 4360/4885L3MBTL1 3913/4885MAOB 3108/4885
US-20070117797-A1 Alkylamino, arylamino, and sulfonamido cyclopentyl amide modulators of chemokine receptor activity CCR7, ACKR3, CCR2 LMNA 4599/4885L3MBTL1 4855/4885MAOB 2710/4885
US-20230212121-A1 SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS SLC6A2, SLC6A3, SLC6A4 LMNA 3772/4885L3MBTL1 4546/4885MAOB 24/4885
US-20080300405-A1 Naphthalenetetracarboxylic Aicd Derivatives and their Use as Semiconductors ADSL, ALAD, EED LMNA 2657/4885L3MBTL1 4486/4885MAOB 3091/4885
US-20190248840-A1 ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS VIP, PREP, DNPEP LMNA 2969/4885L3MBTL1 781/4885MAOB 3290/4885
US-11230571-B2 Anthelmintic depsipeptide compounds VIP, PREP, DNPEP LMNA 2969/4885L3MBTL1 781/4885MAOB 3290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.