SCHEMBL28478111

SCHEMBL28478111

C[Si](C)(CCCCCC1CCCC1)C1CCCCO1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.40
CYP1A2 P05177 1/20 0.37
NAAA Q02083 2/20 0.32
EPHX1 P07099 1/20 0.31
CEL P19835 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28332148 0.83 EPHX1 (0.40) CYP1A2NAAAEPHX1
SCHEMBL8934882 0.83 EPHX1 (0.40) CYP1A2NAAAEPHX1
SCHEMBL28379421 0.83 EPHX1 (0.40) CYP1A2NAAAEPHX1
SCHEMBL2292980 0.83 EPHX1 (0.40) CYP1A2NAAAEPHX1
SCHEMBL3769594 0.83 EPHX1 (0.40) CYP1A2NAAAEPHX1
SCHEMBL28901503 0.81 SIGMAR1 (0.36) SIGMAR1
SCHEMBL28629298 0.81 EPHX1 (0.37) CYP1A2NAAAEPHX1
SCHEMBL11762899 0.79 USP2 (0.30)
SCHEMBL5605591 0.79 EPHX1 (0.34) CYP1A2EPHX1
SCHEMBL9226401 0.78 TSHR (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107041851-B Foundation make-up composition for dark skin color and preparation method thereof 广州智媛生物科技有限公司 2020-11-03 CN disclosed