Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3158871 | 0.85 | HSPB1 (0.55) | MAPTPKMCYP2C19MEN1KMT2A | |
| SCHEMBL28478369 | 0.82 | SMN1; SMN2 (0.51) | MAPTPKMCYP2C19MEN1KMT2A | |
| SCHEMBL28983411 | 0.79 | HSPB1 (0.51) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL20577480 | 0.79 | HSPB1 (0.55) | MAPTPKMMEN1KMT2AALDH1A1 | |
| SCHEMBL580832 | 0.79 | KMT2A (0.41) | MAPTPKMMEN1KMT2AALDH1A1 | |
| SCHEMBL28490331 | 0.79 | CYP2C19 (0.39) | MAPTPKMCYP2C19MEN1KMT2A | |
| SCHEMBL28480773 | 0.77 | KMT2A (0.52) | MAPTPKMCYP2C19MEN1KMT2A | |
| SCHEMBL28475326 | 0.77 | PIN1 (0.55) | MAPTPKMCYP2C19MEN1KMT2A | |
| SCHEMBL1135850 | 0.75 | L3MBTL1 (0.63) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL28477035 | 0.75 | MAPT (0.50) | MAPTCYP2C19MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108164397-B | Catechol derivative and its preparation method | 暨南大学 | 2020-11-13 | — | — | CN | disclosed |