Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | LPL | P06858 | 8/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21177479 | 0.87 | CA2 (0.40) | CA1CA2CA9CSF1RLPL | |
| SCHEMBL23585387 | 0.86 | AAK1 (0.40) | CA1CA2CA9CSF1RLPL | |
| SCHEMBL1790022 | 0.86 | SMN1; SMN2 (0.51) | CA1CA2CA9CSF1RLPL | |
| SCHEMBL32665133 | 0.84 | CA1 (0.44) | CA1CA2CA9CSF1RLPL | |
| SCHEMBL14250498 | 0.84 | CA2 (0.51) | CA1CA2CA9CSF1RCA12 | |
| SCHEMBL25429051 | 0.84 | SMN1; SMN2 (0.56) | CA1CA2CA9CSF1RLPL | |
| SCHEMBL15545140 | 0.82 | L3MBTL1 (0.55) | CA1CA2CA9CSF1RCA12 | |
| SCHEMBL17394139 | 0.82 | CA1 (0.43) | CA1CA2CA9CSF1RLPL | |
| SCHEMBL30519309 | 0.82 | L3MBTL1 (0.55) | CA1CA2CA9CSF1RCA12 | |
| SCHEMBL16015100 | 0.80 | CSF1R (0.43) | CA1CA2CA9CSF1RCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111868063-A | PI4KIII beta inhibitors | 葛兰素史克知识产权开发有限公司 | 2020-10-30 | — | — | CN | disclosed |