Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.44 |
| ▸ | CA2 | P00918 | 5/20 | 0.44 |
| ▸ | CA9 | Q16790 | 5/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | LPL | P06858 | 5/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1790022 | 0.87 | SMN1; SMN2 (0.51) | CA1CA2CA9CSF1RCA12 | |
| SCHEMBL14250498 | 0.86 | CA2 (0.51) | CA1CA2CA9CSF1RCA12 | |
| SCHEMBL28479461 | 0.84 | CA1 (0.43) | CA1CA2CA9CSF1RCA12 | |
| SCHEMBL15545140 | 0.83 | L3MBTL1 (0.55) | CA1CA2CA9CSF1RCA12 | |
| SCHEMBL30519309 | 0.83 | L3MBTL1 (0.55) | CA1CA2CA9CSF1RCA12 | |
| SCHEMBL17394139 | 0.83 | CA1 (0.43) | CA1CA2CA9CSF1RCA12 | |
| SCHEMBL16015100 | 0.81 | CSF1R (0.43) | CA1CA2CA9CSF1RCA12 | |
| SCHEMBL25429051 | 0.80 | SMN1; SMN2 (0.56) | CA1CA2CA9CSF1RCA12 | |
| SCHEMBL21177479 | 0.80 | CA2 (0.40) | CA1CA2CA9CSF1RCA12 | |
| SCHEMBL25430589 | 0.80 | NPSR1 (0.54) | CA1CA2CA9CSF1RCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | CA1 2825/4885CA2 3681/4885CA9 4427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.