Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28478153 | 0.85 | TSHR (0.48) | TSHRMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL28482717 | 0.84 | MEN1 (0.49) | TSHRMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL28480287 | 0.84 | TSHR (0.46) | TSHRMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL28474714 | 0.84 | TSHR (0.46) | TSHRMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL28902155 | 0.83 | TSHR (0.52) | TSHRMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL28901090 | 0.80 | ALDH1A1 (0.52) | TSHRMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL28486339 | 0.76 | CYP19A1 (0.50) | TSHRMEN1KMT2ACYP2C19CYP3A4 | |
| SCHEMBL28482819 | 0.73 | ALDH1A1 (0.46) | TSHRMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL10655087 | 0.71 | TSHR (0.56) | TSHRMEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL10655079 | 0.71 | TSHR (0.56) | TSHRMEN1KMT2ACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483221-B | Method for synthesizing chromone derivative through PhIO-mediated dehydrogenation reaction | 天津大学 | 2020-07-28 | — | — | CN | disclosed |