Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28902155 | 0.85 | TSHR (0.52) | ALDH1A1TDP1CYP2C19MAPTCYP3A4 | |
| SCHEMBL28478153 | 0.81 | TSHR (0.48) | CYP19A1ALDH1A1TDP1CYP2C19SMN1; SMN2 | |
| SCHEMBL28480287 | 0.79 | TSHR (0.46) | CYP19A1ALDH1A1TDP1CYP2C19MAPT | |
| SCHEMBL28482717 | 0.79 | MEN1 (0.49) | CYP19A1ALDH1A1LMNACYP2C19MAPT | |
| SCHEMBL28474714 | 0.79 | TSHR (0.46) | CYP19A1ALDH1A1TDP1CYP2C19SMN1; SMN2 | |
| SCHEMBL28482819 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TDP1CYP2C19MAPTKDM4E | |
| SCHEMBL28480282 | 0.76 | TSHR (0.43) | ALDH1A1TDP1CYP2C19CYP3A4SMN1; SMN2 | |
| SCHEMBL11555749 | 0.75 | ALDH1A1 (0.72) | CYP19A1MAOBALDH1A1TDP1LMNA | |
| SCHEMBL28901090 | 0.75 | ALDH1A1 (0.52) | ALDH1A1LMNACYP2C19MAPTKDM4E | |
| SCHEMBL29397268 | 0.75 | CYP19A1 (0.57) | CYP19A1MAOBALDH1A1LMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483221-B | Method for synthesizing chromone derivative through PhIO-mediated dehydrogenation reaction | 天津大学 | 2020-07-28 | — | — | CN | disclosed |