Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | RET | P07949 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28478153 | 0.88 | TSHR (0.48) | TSHRALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL28480287 | 0.86 | TSHR (0.46) | TSHRALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL28474714 | 0.86 | TSHR (0.46) | TSHRALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL28482717 | 0.86 | MEN1 (0.49) | TSHRALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL28482819 | 0.86 | ALDH1A1 (0.46) | TSHRALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL28486339 | 0.85 | CYP19A1 (0.50) | TSHRALDH1A1MEN1KMT2ACYP2C19 | |
| SCHEMBL28480282 | 0.83 | TSHR (0.43) | TSHRALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL28477163 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ATDP1MAPT | |
| SCHEMBL28473689 | 0.83 | ALDH1A1 (0.48) | TSHRALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL10655087 | 0.82 | TSHR (0.56) | TSHRALDH1A1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483221-B | Method for synthesizing chromone derivative through PhIO-mediated dehydrogenation reaction | 天津大学 | 2020-07-28 | — | — | CN | disclosed |