Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20399476 | 0.82 | GABRA1 (0.49) | KDM4ECALM1TSHRALDH1A1KMT2A | |
| SCHEMBL20399497 | 0.81 | PTGS2 (0.45) | KDM4ECALM1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL28489147 | 0.79 | AKR1B1 (0.50) | KDM4EKMT2AGAAMAPTLMNA | |
| SCHEMBL28492538 | 0.79 | HTT (0.41) | KDM4ECALM1TSHRALDH1A1KMT2A | |
| SCHEMBL10884933 | 0.76 | ALDH1A1 (0.48) | KDM4ETSHRHSD17B10ALDH1A1KMT2A | |
| SCHEMBL18126742 | 0.76 | AKR1B1 (0.51) | CALM1ALDH1A1GAACYP3A4GABRA1 | |
| SCHEMBL20399293 | 0.74 | GABRA1 (0.47) | KDM4ECALM1TSHRALDH1A1KMT2A | |
| SCHEMBL20399502 | 0.74 | NPC1 (0.50) | CALM1CYP3A4GABRA1GABRB2MAPK1 | |
| SCHEMBL31376349 | 0.74 | KDM4E (0.47) | KDM4ETSHRHSD17B10ALDH1A1KMT2A | |
| SCHEMBL10972323 | 0.74 | ALDH1A1 (0.43) | KDM4ETSHRHSD17B10ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440355-B | Thioether compound and synthesis method and application thereof | 浙江大学宁波理工学院 | 2020-11-27 | — | — | CN | disclosed |