Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.58 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4349783 | 0.83 | AKR1B1 (0.53) | FFAR1RXRARXRBRXRGSRD5A2 | |
| SCHEMBL1697834 | 0.78 | FFAR1 (0.68) | FFAR1KEAP1FFAR4HDAC3MAPK1 | |
| SCHEMBL1274096 | 0.77 | KIF11 (0.35) | FFAR1FFAR4 | |
| SCHEMBL30311965 | 0.77 | CA2 (0.46) | — | |
| SCHEMBL1274097 | 0.77 | KIF11 (0.35) | — | |
| SCHEMBL8384151 | 0.76 | FFAR1 (0.51) | FFAR1KEAP1FFAR4HDAC1 | |
| SCHEMBL12394493 | 0.74 | FFAR1 (1.00) | FFAR1KEAP1FFAR4HDAC3MAPK1 | |
| Phenyl Propionic Acid SCHEMBL13618844 | 0.74 | KEAP1 (1.00) | FFAR1KEAP1FFAR4HDAC3MAPK1 | |
| Phenyl Propionic Acid SCHEMBL3419 | 0.74 | KEAP1 (1.00) | FFAR1KEAP1FFAR4HDAC3MAPK1 | |
| Phenyl Propionic Acid SCHEMBL29619843 | 0.74 | KEAP1 (1.00) | FFAR1KEAP1FFAR4HDAC3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111793106-A | Polypeptide helix conformation stabilizing method | 安徽大学 | 2020-10-20 | — | — | CN | claimed |
| CN-111793106-A | Polypeptide helix conformation stabilizing method | 安徽大学 | 2020-10-20 | — | — | CN | disclosed |