SCHEMBL284818

SCHEMBL284818

O=C(OCC1CO1)C1CCCC(C(=O)OCC2CO2)C1

nearest known ligand 0.62

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.62
CYP3A4 P08684 1/20 0.62
ALDH1A1 P00352 2/20 0.44
LMNA P02545 2/20 0.39
MGLL Q99685 2/20 0.39
POLB P06746 1/20 0.38
TSHR P16473 1/20 0.36
ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1277836 0.92 TP53 (0.61) TP53CYP3A4ALDH1A1LMNAMGLL
SCHEMBL10193894 0.90 TP53 (0.56) TP53CYP3A4ALDH1A1LMNAMGLL
SCHEMBL26073524 0.89 TP53 (0.68) TP53CYP3A4ALDH1A1LMNAMGLL
SCHEMBL6358857 0.89 TP53 (0.72) TP53CYP3A4ALDH1A1LMNAMGLL
SCHEMBL12460273 0.88 TP53 (0.60) TP53CYP3A4ALDH1A1LMNAMGLL
SCHEMBL2754958 0.88 TP53 (0.60) TP53CYP3A4ALDH1A1LMNAMGLL
SCHEMBL504165 0.87 TP53 (0.70) TP53CYP3A4ALDH1A1LMNAMGLL
SCHEMBL20492182 0.85 TP53 (0.50) TP53CYP3A4ALDH1A1LMNAMGLL
SCHEMBL285188 0.84 TP53 (0.66) TP53CYP3A4ALDH1A1LMNAMGLL
SCHEMBL7656832 0.84 TP53 (0.66) TP53CYP3A4ALDH1A1LMNAMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2230267-B1 Method of producing a curable epoxy resin composition ABB RESEARCH LTD (CH) 2014-08-13 EP claimed
WO-2013139390-A1 CURABLE EPOXY RESIN COMPOSITION ABB RESEARCH LTD. (CH) 2013-09-26 WO claimed
US-8399577-B2 Curable epoxy resin composition ABB RESEARCH LTD (CH) 2013-03-19 US claimed
US-20120208924-A1 EPOXY RESIN COMPOSITION ABB RESEARCH LTD (CH) 2012-08-16 US claimed
US-20120202918-A1 CURABLE EPOXY RESIN COMPOSITION ABB RESEARCH LTD (CH) 2012-08-09 US claimed
EP-2470583-A1 CURABLE EPOXY RESIN COMPOSITION ABB Research Ltd. (CH) 2012-07-04 EP claimed
US-20120111605-A1 CURABLE SOL-GEL COMPOSITION ABB RESEARCH LTD. (CH) 2012-05-10 US claimed
EP-2427515-A1 CURABLE SOL-GEL COMPOSITION ABB Research Ltd. (CH) 2012-03-14 EP claimed
US-20120025151-A1 CURABLE EPOXY RESIN COMPOSITION ABB RESEARCH LTD (CH) 2012-02-02 US claimed
WO-2011023227-A1 CURABLE EPOXY RESIN COMPOSITION ABB RESEARCH LTD (CH) 2011-03-03 WO claimed
WO-2010127693-A1 CURABLE SOL-GEL COMPOSITION ABB RESEARCH LTD (CH) 2010-11-11 WO claimed
EP-2230267-A1 Curable Epoxy Resin Composition ABB Research Ltd. (CH) 2010-09-22 EP claimed
EP-1354916-A1 Self-hardening epoxy resin for the manufacture of electric insulators ABB RESEARCH LTD. (CH) 2003-10-22 EP claimed
EP-1196508-A1 CURABLE COMPOSITION Vantico AG (CH) 2002-04-17 EP claimed
WO-2001005901-A1 CURABLE COMPOSITION VANTICO AG (CH) 2001-01-25 WO claimed
US-5049631-A Heat resistant SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-09-17 US claimed
EP-4263672-A1 SELF-BLOWING ISOCYANATE-FREE POLYURETHANE FOAMS Université de Liège (BE) 2023-10-25 EP disclosed
US-20230187208-A1 PROTECTIVE FILM-FORMING COMPOSITION CONTAINING DIOL STRUCTURE NISSAN CHEMICAL CORPORATION (JP) 2023-06-15 US disclosed
US-5049631-A Heat resistant SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-09-17 US disclosed
US-5049631-A Heat resistant SHIN-ETSU CHEMICAL CO., LTD. (JP) 1991-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230187208-A1 PROTECTIVE FILM-FORMING COMPOSITION CONTAINING DIOL STRUCTURE DSG1, RAD51, CDH1 TP53 1171/4885CYP3A4 2552/4885ALDH1A1 1697/4885
US-20120208924-A1 EPOXY RESIN COMPOSITION PSMC2, PSMA2, RARG TP53 4320/4885CYP3A4 3373/4885ALDH1A1 736/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.