Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856900 | 0.95 | MAPT (0.47) | MAPTTP53NPSR1CNR1RAB9A | |
| SCHEMBL2857882 | 0.90 | MAPT (0.43) | MAPTTP53NPSR1CNR1RAB9A | |
| SCHEMBL2856513 | 0.90 | TAAR1 (0.51) | MAPTTP53RAB9ATAAR1LMNA | |
| SCHEMBL2860461 | 0.90 | TAAR1 (0.54) | MAPTTP53CNR1RAB9ATAAR1 | |
| SCHEMBL2850486 | 0.89 | MAPT (0.46) | MAPTRAB9ATAAR1LMNAPKM | |
| SCHEMBL2852485 | 0.89 | ABCB1 (0.50) | MAPTTP53NPSR1CNR1TAAR1 | |
| SCHEMBL2858349 | 0.88 | CNR1 (0.44) | MAPTCNR1TAAR1LMNAPKM | |
| SCHEMBL2854313 | 0.87 | NPSR1 (0.54) | MAPTTP53NPSR1CNR1TAAR1 | |
| SCHEMBL2855797 | 0.87 | CNR1 (0.47) | MAPTNPSR1CNR1TAAR1LMNA | |
| SCHEMBL2856544 | 0.86 | ABCB1 (0.53) | TP53CNR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |