Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857882 | 0.95 | MAPT (0.43) | MAPTTAAR1LMNAPKMSMO | |
| SCHEMBL2848346 | 0.95 | MAPT (0.55) | MAPTTAAR1LMNAPKMTP53 | |
| SCHEMBL2856513 | 0.95 | TAAR1 (0.51) | MAPTTAAR1LMNAPKMTP53 | |
| SCHEMBL2860461 | 0.95 | TAAR1 (0.54) | MAPTTAAR1LMNAPKMTP53 | |
| SCHEMBL2850486 | 0.94 | MAPT (0.46) | MAPTTAAR1LMNAPKMSMO | |
| SCHEMBL2858349 | 0.92 | CNR1 (0.44) | MAPTTAAR1LMNAPKMSMO | |
| SCHEMBL2855797 | 0.91 | CNR1 (0.47) | MAPTTAAR1LMNAPKMSMO | |
| SCHEMBL2856544 | 0.91 | ABCB1 (0.53) | LMNATP53ABCB1CNR1SMN1; SMN2 | |
| SCHEMBL2850361 | 0.90 | ABCB1 (0.48) | MAPTTAAR1LMNAPKMNPC1 | |
| SCHEMBL2855564 | 0.89 | CNR1 (0.48) | MAPTTAAR1LMNAPKMSMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |