Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2859179 | 0.91 | ALDH1A1 (0.51) | ALDH1A1LMNA | |
| SCHEMBL2856900 | 0.91 | MAPT (0.47) | ABCB1GAACNR1LMNASMN1; SMN2 | |
| SCHEMBL2858349 | 0.89 | CNR1 (0.44) | ABCB1GAAALDH1A1CNR1LMNA | |
| SCHEMBL2855564 | 0.88 | CNR1 (0.48) | ABCB1GAAALDH1A1CNR1LMNA | |
| SCHEMBL2855797 | 0.88 | CNR1 (0.47) | ABCB1GAACNR1LMNASMN1; SMN2 | |
| SCHEMBL2853116 | 0.88 | CNR1 (0.51) | ABCB1ALDH1A1CNR1 | |
| SCHEMBL2850361 | 0.87 | ABCB1 (0.48) | ABCB1GAAALDH1A1CNR1LMNA | |
| SCHEMBL2857882 | 0.86 | MAPT (0.43) | ABCB1CNR1LMNASMN1; SMN2TP53 | |
| SCHEMBL2848346 | 0.86 | MAPT (0.55) | CNR1LMNATP53 | |
| SCHEMBL2856513 | 0.86 | TAAR1 (0.51) | ABCB1GAAALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |