Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | FPR3 | P25089 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854676 | 0.91 | ALDH1A1 (0.45) | SMN1; SMN2RAB9AALDH1A1HTTKDM4E | |
| SCHEMBL2855547 | 0.87 | TAAR1 (0.54) | SMN1; SMN2CNR1POLBRAB9AALDH1A1 | |
| SCHEMBL2860669 | 0.85 | TAAR1 (0.46) | CNR1ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL2857987 | 0.85 | CNR1 (0.43) | SMN1; SMN2CNR1POLBALDH1A1KDM4E | |
| SCHEMBL2859861 | 0.85 | TAAR1 (0.51) | SMN1; SMN2CNR1POLBALDH1A1HTT | |
| SCHEMBL2858012 | 0.84 | CNR1 (0.46) | SMN1; SMN2CNR1POLBALDH1A1KDM4E | |
| SCHEMBL2858371 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2CNR1POLBRAB9AALDH1A1 | |
| SCHEMBL2858618 | 0.84 | ALDH1A1 (0.41) | SMN1; SMN2CNR1POLBALDH1A1KDM4E | |
| SCHEMBL2860468 | 0.84 | KDM4E (0.44) | CNR1KDM4EMAPTLMNAMAPK1 | |
| SCHEMBL2854517 | 0.83 | MAPT (0.42) | SMN1; SMN2CNR1POLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |