Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.37 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.37 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.37 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.37 |
| ▸ | STIM2 | Q9P246 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860131 | 0.92 | ALDH1A1 (0.46) | MAPTRXFP1KDM4EALDH1A1NPSR1 | |
| SCHEMBL2856750 | 0.92 | P2RX7 (0.42) | MAPTCCR1RXFP1KDM4EALDH1A1 | |
| SCHEMBL2857987 | 0.91 | CNR1 (0.43) | MAPTCCR1RXFP1CNR1KDM4E | |
| SCHEMBL2859365 | 0.90 | CNR1 (0.49) | MAPTCNR1KDM4EALDH1A1TAAR1 | |
| SCHEMBL2858012 | 0.90 | CNR1 (0.46) | MAPTCCR1RXFP1CNR1KDM4E | |
| SCHEMBL2858267 | 0.89 | MAPT (0.41) | MAPTCCR1ALDH1A1HSP90AA1NPSR1 | |
| SCHEMBL2855547 | 0.87 | TAAR1 (0.54) | MAPTCCR1CNR1KDM4EALDH1A1 | |
| SCHEMBL2860669 | 0.85 | TAAR1 (0.46) | MAPTCCR1CNR1KDM4EALDH1A1 | |
| SCHEMBL2855322 | 0.85 | P2RX7 (0.47) | MAPTCCR1CNR1KDM4EALDH1A1 | |
| SCHEMBL2859861 | 0.85 | TAAR1 (0.51) | MAPTCNR1KDM4EALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |