Oxirane

Oxirane

SCHEMBL28484136

C1CO1.CC(C)c1ccc(O)c(C(C)C)c1C(C)C

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 5/20 0.40
HSP90AB1 P08238 4/20 0.40
LMNA P02545 2/20 0.39
SLC6A2 P23975 2/20 0.39
HTR2B P41595 2/20 0.39
TRPA1 O75762 1/20 0.39
CHRM1 P11229 1/20 0.39
ADRA1A P35348 1/20 0.39
GABRA1 P14867 3/20 0.39
GABRB2 P47870 3/20 0.39
CYP3A4 P08684 3/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
HIF1A Q16665 2/20 0.35
FAAH O00519 1/20 0.35
CYP1A2 P05177 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
GABRB1 P18505 1/20 0.35
GABRG2 P18507 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL478565 0.89 LMNA (0.46) HSP90AA1HSP90AB1LMNASLC6A2HTR2B
Benzene SCHEMBL1834239 0.85 GABRA1 (0.48) HSP90AA1HSP90AB1LMNASLC6A2HTR2B
Phosphoric Acid SCHEMBL7620701 0.80 LMNA (0.39) HSP90AA1HSP90AB1LMNASLC6A2HTR2B
SCHEMBL30360391 0.78 TYR (0.44) HSP90AA1HSP90AB1LMNASLC6A2HTR2B
SCHEMBL1760433 0.78 TYR (0.44) HSP90AA1HSP90AB1LMNASLC6A2HTR2B
SCHEMBL1292825 0.75 GABRA1 (0.41) LMNASLC6A2HTR2BTRPA1CHRM1
SCHEMBL16527874 0.74 LMNA (0.45) HSP90AA1HSP90AB1LMNASLC6A2HTR2B
SCHEMBL6679675 0.74 GABRA1 (0.52) HSP90AA1HSP90AB1LMNASLC6A2HTR2B
SCHEMBL6015493 0.74 GABRA1 (0.46) LMNASLC6A2HTR2BTRPA1CHRM1
SCHEMBL16528078 0.74 LMNA (0.45) HSP90AA1HSP90AB1LMNASLC6A2HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106087464-B Dyeing and printing process 沈阳化工研究院有限公司 2020-08-14 CN disclosed