Phosphoric Acid

Phosphoric Acid

SCHEMBL7620701

CC(C)c1ccc(O)c(C(C)C)c1C(C)C.O=P(O)(O)O

nearest known ligand 0.39

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA1A known ✓ P35348 1/20 0.39
LMNA P02545 2/20 0.39
SLC6A2 P23975 2/20 0.39
HTR2B P41595 2/20 0.39
TRPA1 O75762 1/20 0.39
CHRM1 P11229 1/20 0.39
GABRA1 P14867 2/20 0.39
GABRB2 P47870 2/20 0.39
HSP90AA1 P07900 1/20 0.37
HSP90AB1 P08238 1/20 0.37
THRA P10827 13/20 0.36
THRB P10828 13/20 0.36
FAAH O00519 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
GABRB1 P18505 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL478565 0.89 LMNA (0.46) LMNASLC6A2HTR2BTRPA1CHRM1
Benzene SCHEMBL1834239 0.85 GABRA1 (0.48) LMNASLC6A2HTR2BTRPA1CHRM1
Oxirane SCHEMBL28484136 0.80 HSP90AA1 (0.40) LMNASLC6A2HTR2BTRPA1CHRM1
SCHEMBL30360391 0.78 TYR (0.44) LMNASLC6A2HTR2BTRPA1CHRM1
SCHEMBL1760433 0.78 TYR (0.44) LMNASLC6A2HTR2BTRPA1CHRM1
Phosphoric Acid SCHEMBL28178732 0.77 GABRA1 (0.50) LMNASLC6A2HTR2BGABRA1GABRB2
SCHEMBL1292825 0.75 GABRA1 (0.41) LMNASLC6A2HTR2BTRPA1CHRM1
SCHEMBL6679675 0.74 GABRA1 (0.52) LMNASLC6A2HTR2BTRPA1CHRM1
SCHEMBL16527874 0.74 LMNA (0.45) LMNASLC6A2HTR2BTRPA1CHRM1
SCHEMBL6015493 0.74 GABRA1 (0.46) LMNASLC6A2HTR2BTRPA1CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6436883-B1 LIQUID COMPOSITION WHICH CONSISTS ESSENTIALLY OF WATER SOLUBLE POLYOXYALKYLENE GLYCOL MONOBUTYL ETHER HAVING SPECIFIED MOLECULAR WEIGHT AND VISCOSITY, CARBOXYLIC ACID, AMINE HUNTSMAN PETROCHEMICAL CORPORATION 2002-08-20 US claimed