SCHEMBL28484191

SCHEMBL28484191

CCC(CCCCCCCNC(=O)O)NC(=O)O

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 8/20 0.40
KDM4E B2RXH2 1/20 0.38
MAPK1 P28482 1/20 0.38
HIF1A Q16665 1/20 0.38
GNAI3 P08754 1/20 0.37
GNAO1 P09471 1/20 0.37
GNAI1 P63096 1/20 0.37
SIRT6 Q8N6T7 1/20 0.37
SIRT1 Q96EB6 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
RRM1 P23921 1/20 0.36
FOLH1 Q04609 1/20 0.36
CASP2 P42575 1/20 0.35
ADRA1A P35348 1/20 0.35
DPP7 Q9UHL4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17141303 0.86 DPP7 (0.42) EPHX1GNAI3GNAO1GNAI1SIRT6
SCHEMBL28960765 0.85 CYP2D6 (0.37) KDM4ESMN1; SMN2ADRA1A
SCHEMBL6154715 0.83 PLA2G2C (0.49)
SCHEMBL28618729 0.83 PLA2G2C (0.49)
SCHEMBL11292593 0.83 PLA2G2C (0.49)
SCHEMBL27992370 0.83 PLA2G2C (0.49)
SCHEMBL27793369 0.83 PLA2G2C (0.49)
SCHEMBL11168552 0.83 PLA2G2C (0.49)
SCHEMBL28866263 0.82 CA2 (0.40) MAPK1
SCHEMBL8570438 0.82 ALDH1A1 (0.34) EPHX1KDM4EMAPK1HIF1AGNAI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112011049-A Thermoplastic polyurea elastomer and preparation method thereof 中国科学院化学研究所 2020-12-01 CN disclosed