SCHEMBL28484716

SCHEMBL28484716

COC1c2ccccc2OC(c2ccccc2)C1O

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 2/20 0.40
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
ELANE P08246 1/20 0.35
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ADRA1A P35348 1/20 0.33
GUSB P08236 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28735519 0.84 ESR2 (0.45) ESR1ESR2MAOAMAOBMEN1
SCHEMBL170331 0.78 MAOA (0.41) NR3C1ESR1ESR2MAOAMAOB
SCHEMBL30775734 0.78 MAOA (0.41) NR3C1ESR1ESR2MAOAMAOB
SCHEMBL1257771 0.78 MAOA (0.41) NR3C1ESR1ESR2MAOAMAOB
SCHEMBL25669484 0.75 MAOA (0.38) NR3C1ESR1ESR2MAOAMAOB
SCHEMBL7241380 0.75 MAOA (0.38) NR3C1ESR1ESR2MAOAMAOB
SCHEMBL8340999 0.73 MAOA (0.34) NR3C1ESR1ESR2MAOAMAOB
SCHEMBL2967633 0.72 GABRA1 (0.46) MAOBMEN1KMT2AALDH1A1
SCHEMBL13287870 0.71 MAOB (0.38) NR3C1ESR1ESR2MAOAMAOB
SCHEMBL10037557 0.70 CYP3A4 (0.44) NR3C1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108410886-B Biosynthesis and detection method of catechin intermediate 安徽农业大学 2020-11-13 CN disclosed