SCHEMBL2967633

SCHEMBL2967633

COc1ccc(C2Oc3ccccc3C(O)C2O)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.46
GABRB2 P47870 2/20 0.46
CYP3A4 P08684 3/20 0.45
MAPK1 P28482 1/20 0.45
EDNRA P25101 3/20 0.43
EDNRB P24530 2/20 0.43
MAPT P10636 3/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
MAOB P27338 1/20 0.42
MEN1 O00255 2/20 0.41
POLB P06746 2/20 0.41
HTT P42858 2/20 0.41
KMT2A Q03164 2/20 0.41
THRB P10828 1/20 0.41
BLM P54132 1/20 0.41
CBS P35520 1/20 0.40
ALDH1A1 P00352 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11212671 0.85 GABRA1 (0.44) GABRA1GABRB2CYP3A4MAPK1EDNRA
SCHEMBL6864759 0.82 CYP2C19 (0.49) CYP3A4MAPK1MAPTNPC1RAB9A
SCHEMBL170331 0.82 MAOA (0.41) EDNRAMAPTMAOBMEN1KMT2A
SCHEMBL30775734 0.82 MAOA (0.41) EDNRAMAPTMAOBMEN1KMT2A
SCHEMBL1257771 0.82 MAOA (0.41) EDNRAMAPTMAOBMEN1KMT2A
SCHEMBL11342705 0.81 EDNRA (0.42) GABRA1GABRB2CYP3A4MAPK1EDNRA
SCHEMBL29066395 0.78 CYP3A4 (0.40) CYP3A4MAPK1EDNRAEDNRBMAPT
SCHEMBL10367170 0.75 MAOB (0.48) CYP3A4MAPTNPC1RAB9AMAOB
SCHEMBL10694325 0.74 EDNRA (0.49) GABRA1GABRB2EDNRAEDNRBMAPT
SCHEMBL10694317 0.74 EDNRA (0.49) GABRA1GABRB2EDNRAEDNRBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113136026-A Forming method of sealed shell for photoelectric sensor 杭州安誉科技有限公司 2021-07-20 CN claimed
CN-112423600-A Taste modifier composition, beverage and flavouring composition thereof 阿尔门德拉私人有限公司 2021-02-26 CN claimed
CN-116637102-B Application of flavane compound in preparation of antitumor drugs 北京中医药大学 2024-04-09 CN disclosed
CN-116637102-A Application of flavane compound in preparation of antitumor drugs 北京中医药大学 2023-08-25 CN disclosed
CN-113509459-B Application of flavane compound in preparation of antitumor drugs 北京中医药大学 2023-07-28 CN disclosed
CN-113509459-A Application of flavane compound in preparing anti-tumor medicine 北京中医药大学 2021-10-19 CN disclosed
CN-113136026-A Forming method of sealed shell for photoelectric sensor 杭州安誉科技有限公司 2021-07-20 CN disclosed
CN-112423600-A Taste modifier composition, beverage and flavouring composition thereof 阿尔门德拉私人有限公司 2021-02-26 CN disclosed
EP-2253226-B1 Use of hydroxyflavone derivatives for modifying taste LEIBNIZ INST FÜR PFLANZENBIOCHEMIE IPB (DE) 2015-07-15 EP disclosed
EP-2253226-A1 Use of hydroxyflavone derivatives for modifying taste Leibniz-Institut für Pflanzenbiochemie (IPB) (DE) 2010-11-24 EP disclosed
US-20100292175-A1 USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION Leibniz-Institut fur Pflanzenbiochemie (DE) 2010-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100292175-A1 USE OF HYDROXYFLAVAN DERIVATIVES FOR TASTE MODIFICATION TAS2R50, TAS2R60, TAS2R30 GABRA1 1590/4885GABRB2 686/4885CYP3A4 1777/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.