Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28902448 | 0.83 | KMT2A (0.53) | ALDH1A1KMT2AMAPTMEN1RAB9A | |
| SCHEMBL2081799 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDKMT2AADRB2 | |
| SCHEMBL28482764 | 0.79 | MAPT (0.43) | ALDH1A1KDM4EKMT2AADRB2ADRB1 | |
| SCHEMBL28493049 | 0.71 | NPC1 (0.44) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL28489348 | 0.70 | KMT2A (0.43) | ALDH1A1KDM4EHPGDKMT2AMAPT | |
| SCHEMBL22838115 | 0.70 | SLC6A3 (0.49) | ALDH1A1KDM4EKMT2AADRB2ADRB1 | |
| SCHEMBL5724096 | 0.70 | MAPT (0.49) | ALDH1A1KDM4EHPGDKMT2AADRB2 | |
| SCHEMBL27559505 | 0.69 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDKMT2AADRB2 | |
| SCHEMBL27771673 | 0.69 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDKMT2AADRB2 | |
| SCHEMBL550633 | 0.69 | KMT2A (0.52) | ALDH1A1KDM4EHPGDKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651286-B | High-selectivity synthesis method of 4- (4-aminophenyl) morpholine-3-one | 新发药业有限公司 | 2020-08-11 | — | — | CN | disclosed |